SCHEMBL437366

SCHEMBL437366

N#Cc1ccnc(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30372755 1.00
SCHEMBL29620507 0.79 CLK4 (0.59)
SCHEMBL23228524 0.79 CLK4 (0.59)
SCHEMBL432380 0.77
SCHEMBL3841170 0.77
SCHEMBL30823015 0.77
SCHEMBL29500425 0.76 NPY5R (0.45)
SCHEMBL9792784 0.76 NPY5R (0.45)
SCHEMBL29598148 0.74 CLK4 (0.44)
SCHEMBL995799 0.74 CLK4 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805172-B Method for synthesizing asymmetric heterocyclic diaryl methane compound 陇东学院 2024-04-23 CN claimed
CN-113717151-B Pure organic room temperature phosphorescent compound, preparation method and application thereof 北京化工大学 2023-12-15 CN claimed
CN-114361590-B Electrolyte additive for lithium ion battery, electrolyte and lithium ion battery 松山湖材料实验室 2023-07-25 CN claimed
CN-114361590-A Lithium ion battery electrolyte additive, electrolyte and lithium ion battery 松山湖材料实验室 2022-04-15 CN claimed
CN-112886059-A Lithium ion battery electrolyte containing imidazole compound 石家庄圣泰化工有限公司 2021-06-01 CN claimed
WO-2020127887-A1 PROCESS FOR THE PREPARATION OF AN INTERMEDIATE PRODUCT OF IVOSIDENIB SANDOZ AG (CH) 2020-06-25 WO claimed
EP-4747258-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics, Inc. (US) 2026-05-27 EP disclosed
EP-4687883-A2 MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE Caraway Therapeutics, Inc. (US) 2026-02-11 EP disclosed
EP-4661863-A2 MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE Caraway Therapeutics, Inc. (US) 2025-12-17 EP disclosed
EP-4661864-A2 MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE Caraway Therapeutics, Inc. (US) 2025-12-17 EP disclosed
EP-4630404-A1 UREA COMPOUNDS AS ACTIVATORS OF POTASSIUM CHANNELS KV7.2/7.3 USEFUL IN THE TREATMENT OF CNS AND PNS DISORDERS ANGELINI PHARMA S.P.A. (IT) 2025-10-15 EP disclosed
EP-4630406-A1 AMIDE COMPOUNDS AS ACTIVATORS OF THE POTASSIUM CHANNELS KV7.2/KV7.3 USEFUL IN THE TREATMENT OF CNS AND PNS DISORDERS ANGELINI PHARMA S.P.A. (IT) 2025-10-15 EP disclosed
EP-4624465-A1 COMPOUND SERVING AS DDR1 KINASE INHIBITOR, AND MEDICINE Nippon Shinyaku Co., Ltd. (JP) 2025-10-01 EP disclosed
EP-1233010-B1 Method for production of organic fluorine compound NIPPON CATALYTIC CHEM IND (JP) 2005-06-15 EP disclosed
EP-0899256-B1 Method for production of organic fluorine compound NIPPON CATALYTIC CHEM IND (JP) 2003-08-06 EP disclosed
EP-1233010-A1 Method for production of organic fluorine compound Nippon Shokubai Co., Ltd. (JP) 2002-08-21 EP disclosed
US-6392084-B1 FLUORINATION OF AN ORGANO(BROMINE OR CHLORIDE) COMPOUND IN BENZONITRILE SOLVENT NIPPON SHOKUBAI CO., LTD. (JP) 2002-05-21 US disclosed
EP-0899256-A2 Method for production of organic fluorine compound NIPPON SHOKUBAI CO., LTD. (JP) 1999-03-03 EP disclosed
US-4684734-A Method for manufacture or organic fluorine compounds NIPPON SHOKUBAI KK CO., LTD. (JP) 1987-08-04 US disclosed
EP-0120575-A1 Organic fluorine compounds Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1984-10-03 EP disclosed