Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.70 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.70 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.70 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.70 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.70 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.70 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844474 | 0.83 | HDAC3 (1.00) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13270940 | 0.83 | MAPT (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL21688074 | 0.81 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8113597 | 0.81 | HDAC3 (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5744739 | 0.81 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20622475 | 0.81 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19870991 | 0.80 | KCNN4 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3739537 | 0.79 | HDAC3 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1978837 | 0.79 | POLB (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7720891 | 0.79 | HDAC3 (0.66) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121575-A2 | LERCANIDIPINE HYDROCHLORIDE POLYMORPHS AND AN IMPROVED PROCESS FOR PREPARATION OF 1,1,N-TRIMETHYL-N-(3,3-DIPHENYLPROPYL)-2-AMINOETHYL ACETOACETATE | Actavis Group PTC EHF (IS) | 2009-11-25 | — | — | EP | claimed |
| WO-2008107797-A2 | LERCANIDIPINE HYDROCHLORIDE POLYMORPHS AND AN IMPROVED PROCESS FOR PREPARATION OF 1,1,N-TRIMETHYL-N-(3,3-DIPHENYLPROPYL)-2-AMINOETHYL ACETOACETATE | ACTAVIS GROUP PTC EHF (IS) | 2008-09-12 | — | — | WO | claimed |
| EP-3424960-A1 | POLYMER PRODUCTION METHOD AND RADICAL POLYMERIZATION INITIATING GROUP-CONTAINING COMPOUND | Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) | 2019-01-09 | — | — | EP | disclosed |
| CN-108026230-A | Antifouling composition | 巴斯夫欧洲公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-107922571-A | Antifouling composition | 巴斯夫欧洲公司 | 2018-04-17 | — | — | CN | disclosed |
| EP-1933621-A1 | HERBICIDE COMPOSITION | NUFARM AUSTRALIA LIMITED (AU) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007030887-A1 | HERBICIDE COMPOSITION | NUFARM AUSTRALIA LIMITED (AU) | 2007-03-22 | — | — | WO | disclosed |
| EP-0923288-A1 | HERBICIDES BASED ON 4-BROMO-1-METHYL-5-TRIFLUOROMETHYL-3-(2-FLUORO-4-CHLORO-5-ISOPROPOXYCARBONYLPHENYL)PYRAZOLE | BAYER AG (DE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008383-A1 | HERBICIDES BASED ON 4-BROMO-1-METHYL-5-TRIFLUOROMETHYL-3-(2-FLUORO-4-CHLORO-5-ISOPROPOXYCARBONYLPHENYL)PYRAZOLE | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-05 | — | — | WO | disclosed |
| EP-0368592-A1 | Herbicidal compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-16 | — | — | EP | disclosed |
| CN-87103510-A | Substituted pyridine herbicide | — | 1988-01-20 | — | — | CN | disclosed |
| EP-0248554-A2 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-12-09 | — | — | EP | disclosed |
| EP-0009419-B1 | AGRICULTURAL SULFONAMIDES, AND PREPARATION AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-02 | — | — | EP | disclosed |