Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | DDO | Q99489 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | CHUK | O15111 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15962870 | 0.82 | AXL (0.53) | AXLPRKCIDAODDOIKBKB | |
| SCHEMBL26262641 | 0.74 | RET (0.42) | RETKDR | |
| SCHEMBL13507207 | 0.72 | IKBKB (0.46) | IKBKBCHUKRETKDR | |
| SCHEMBL3413744 | 0.71 | IKBKB (0.45) | AXLPRKCIDAOIKBKBCHUK | |
| SCHEMBL31420487 | 0.71 | IKBKB (0.45) | AXLPRKCIDAOIKBKBCHUK | |
| SCHEMBL16908345 | 0.70 | IKBKB (0.35) | IKBKBCHUK | |
| SCHEMBL16977985 | 0.68 | KIT (0.54) | AXLPRKCI | |
| SCHEMBL25449356 | 0.67 | PI4KA (0.40) | IKBKBCHUKRETKDR | |
| SCHEMBL4050239 | 0.67 | CCR1 (0.39) | RETKDR | |
| SCHEMBL25666628 | 0.67 | IKBKB (0.36) | IKBKBCHUKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009112473-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-09-17 | — | — | WO | disclosed |
| WO-2009112473-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-09-17 | — | — | WO | disclosed |