Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | TTR | P02766 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | JUN | P05412 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4368151 | 1.00 | F3 (0.65) | F3LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4373949 | 1.00 | F3 (0.65) | F3LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4370893 | 1.00 | F3 (0.65) | F3LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4369837 | 0.98 | F3 (0.67) | F3LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5598768 | 0.98 | F3 (0.67) | F3LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL609972 | 0.86 | GSK3B (0.71) | F3LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL609973 | 0.86 | GSK3B (0.71) | F3LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2451780 | 0.86 | MAPT (0.81) | F3LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10941162 | 0.86 | MAPT (0.81) | F3LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11354408 | 0.86 | MAPT (0.81) | F3LMNAKMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436197-B2 | Palladium complexes and polymerization and coupling processes thereof | WEST CHESTER UNIVERSITY OF PENNSYLVANIA OF THE STATE SYSTEM OF HIGHER EDUCATION (US) | 2013-05-07 | — | — | US | claimed |
| US-20090111962-A1 | Palladium Complexes and Polymerization and Coupling Processes Thereof | WEST CHESTER UNIVERSITY OF PENNSYLVANIA OF THE STATE SYSTEM OF HIGHER EDUCATION | 2009-04-30 | — | — | US | claimed |
| WO-2016029216-A2 | METHOD FOR PRODUCING AMIDINE DERIVATIVES | BIOCRYST PHARMACEUTICALS, INC. (US) | 2016-02-25 | — | — | WO | disclosed |
| US-8436197-B2 | Palladium complexes and polymerization and coupling processes thereof | WEST CHESTER UNIVERSITY OF PENNSYLVANIA OF THE STATE SYSTEM OF HIGHER EDUCATION (US) | 2013-05-07 | — | — | US | disclosed |
| US-20090111962-A1 | Palladium Complexes and Polymerization and Coupling Processes Thereof | WEST CHESTER UNIVERSITY OF PENNSYLVANIA OF THE STATE SYSTEM OF HIGHER EDUCATION | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111962-A1 | Palladium Complexes and Polymerization and Coupling Processes Thereof | DDT, PDCD2L, PDCD1LG2 | F3 1590/4885LMNA 4360/4885KMT2A 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.