Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929928 | 0.82 | HTT (0.67) | HTTTDP1ERN1SMN1; SMN2LMNA | |
| SCHEMBL29745600 | 0.78 | HTT (0.58) | HTTTDP1ERN1SMN1; SMN2LMNA | |
| SCHEMBL6676325 | 0.78 | SMN1; SMN2 (0.57) | HTTTDP1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7517823 | 0.78 | HTT (0.58) | HTTTDP1ERN1SMN1; SMN2LMNA | |
| SCHEMBL29407238 | 0.77 | HTT (0.66) | HTTTDP1ERN1SMN1; SMN2LMNA | |
| SCHEMBL477199 | 0.77 | HTT (0.66) | HTTTDP1ERN1SMN1; SMN2LMNA | |
| SCHEMBL31405107 | 0.76 | HTT (0.59) | HTTTDP1ERN1SMN1; SMN2LMNA | |
| SCHEMBL29406556 | 0.76 | HTT (0.59) | HTTTDP1ERN1LMNAALDH1A1 | |
| SCHEMBL11524810 | 0.76 | HTT (0.59) | HTTTDP1ERN1LMNAALDH1A1 | |
| SCHEMBL5159243 | 0.76 | HTT (0.59) | HTTTDP1ERN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074986-B1 | Process for treating hair fibres using polysiloxane/polyurea | OREAL (FR) | 2013-05-15 | — | — | EP | disclosed |
| EP-2074986-A1 | Process for treating hair fibres using polysiloxane/polyurea | L'Oréal (FR) | 2009-07-01 | — | — | EP | disclosed |
| EP-1935404-A1 | Composition for dyeing keratinous fibres comprising a polysiloxane-polyurea block copolymer | L'Oréal (FR) | 2008-06-25 | — | — | EP | disclosed |
| EP-1844816-A2 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'Oréal (FR) | 2007-10-17 | — | — | EP | disclosed |