Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.72 |
| ▸ | HTR2C | P28335 | 10/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039637 | 0.91 | HTR2A (0.67) | HTR2AHTR2CKCNH2 | |
| SCHEMBL4566174 | 0.90 | HTR2A (0.70) | HTR2AHTR2CKCNH2 | |
| SCHEMBL884063 | 0.88 | HTR2A (0.73) | HTR2AHTR2CKCNH2 | |
| SCHEMBL883985 | 0.84 | HTR2A (1.00) | HTR2AHTR2CKCNH2 | |
| SCHEMBL885418 | 0.82 | HTR2A (0.75) | HTR2AHTR2CKCNH2 | |
| SCHEMBL885424 | 0.82 | HTR2A (0.77) | HTR2AHTR2CKCNH2 | |
| SCHEMBL2066322 | 0.81 | HTR2A (0.74) | HTR2AHTR2CKCNH2 | |
| SCHEMBL2065221 | 0.81 | HTR2A (0.73) | HTR2AHTR2CKCNH2 | |
| SCHEMBL884368 | 0.80 | HTR2A (0.80) | HTR2AHTR2CKCNH2 | |
| SCHEMBL885423 | 0.80 | HTR2A (0.78) | HTR2AHTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027119-A2 | ETHERS, SECONDARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007136680-A2 | 3-PYRAZ0LYL-BENZAMIDE-4-ETHERS, SECONDARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |