⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5984121 | 0.82 | — | — | |
| SCHEMBL231308 | 0.81 | — | — | |
| SCHEMBL625211 | 0.79 | TDP1 (0.32) | — | |
| SCHEMBL20609970 | 0.78 | TSHR (0.46) | — | |
| SCHEMBL149818 | 0.78 | — | — | |
| SCHEMBL232097 | 0.78 | — | — | |
| SCHEMBL620976 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL25386399 | 0.77 | FFAR1 (0.36) | — | |
| SCHEMBL10316599 | 0.77 | FFAR1 (0.36) | — | |
| SCHEMBL3891070 | 0.77 | FFAR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3911 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667631-B2 | FGFR4 inhibitor, preparation method therefor, and applications thereof | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-06-06 | — | — | US | claimed |
| CN-115224197-A | Application of D-pi-A type passivation molecules taking benzotriazoles as donors in perovskite solar cell | 大连理工大学 | 2022-10-21 | — | — | CN | claimed |
| EP-2360143-B1 | SULFONE COMPOUNDS FOR USE AS SOLVENT FOR ELECTROCHEMICAL DEVICES | SUMITOMO SEIKA CHEMICALS (JP) | 2017-08-16 | — | — | EP | claimed |
| WO-2016037223-A1 | DIRHODIUM COMPOUNDS AND METHODS OF USE | GHANEM ASHRAF (AU) | 2016-03-17 | — | — | WO | claimed |
| CN-102216264-B | Sulfone compound | SUMITOMO SEIKA CHEMICALS | 2014-01-15 | — | — | CN | claimed |
| US-8466324-B2 | Sulfone compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2013-06-18 | — | — | US | claimed |
| US-20130087745-A1 | SOLUBLE PRECURSORS AND SOLUTION-BASED PROCESSES FOR PHOTOVOLTAICS | PRECURSOR ENERGETICS, INC. (US) | 2013-04-11 | — | — | US | claimed |
| WO-2008084046-A1 | PLASTICIZERS FOR POLYVINYL ACETALS AND POLYSULFIDES | BASF SE (DE) | 2008-07-17 | — | — | WO | claimed |
| WO-2006065842-A2 | 5,6,7,8-TETRAHYDROQUINOLINES AND RELATED COMPOUNDS AND USES THEREOF | SYNTA PHARMACEUTICALS CORP. (US) | 2006-06-22 | — | — | WO | claimed |
| EP-1663227-A2 | DIHYDROPYRIDINE COMPOUNDS FOR TREATING OR PREVENTING METABOLIC DISORDERS | Synta Pharmaceuticals Corporation (US) | 2006-06-07 | — | — | EP | claimed |
| US-20050203119-A1 | Dihydropyridine compounds for treating or preventing metabolic disorders | SYNTA PHARMACEUTICAL CORP. | 2005-09-15 | — | — | US | claimed |
| WO-2005025507-A2 | DIHYDROPYRIDINE COMPOUNDS FOR TREATING OR PREVENTING METABOLIC DISORDERS | SYNTA PHAMACEUTICALS CORP. (US) | 2005-03-24 | — | — | WO | claimed |
| WO-2024148932-A1 | EGFR C797S MUTATION INHIBITOR AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2024-07-18 | — | — | WO | disclosed |
| CN-114845739-B | Pharmaceutical conjugate of eribulin derivative, preparation method and application thereof in medicine | 上海森辉医药有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113939516-B | Methods and compositions for targeting protein degradation | 珃诺生物医药科技(杭州)有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118324761-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-4081478-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4073808-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |