Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31757251 | 0.89 | AR (0.56) | ARTBXA2REPAS1CYP1A2CYP3A4 | |
| SCHEMBL25355415 | 0.84 | AR (0.55) | ARTBXA2RLRRK2EPAS1SLC6A4 | |
| SCHEMBL11602645 | 0.84 | CYP1A2 (0.48) | ARTBXA2REPAS1CYP1A2CYP3A4 | |
| SCHEMBL8826047 | 0.83 | AR (0.56) | ARLRRK2EPAS1CYP1A2CYP2C19 | |
| SCHEMBL4374224 | 0.81 | AR (0.57) | ARTBXA2RSCN8ASCN10ASLC6A4 | |
| SCHEMBL922953 | 0.80 | AR (0.62) | ARTBXA2RLRRK2EPAS1ALDH1A1 | |
| SCHEMBL27438050 | 0.79 | AR (0.60) | ARLRRK2SLC6A4 | |
| SCHEMBL5837567 | 0.78 | HTR2A (0.65) | ARLRRK2SLC6A4HTR2AKCNH2 | |
| SCHEMBL378936 | 0.78 | LRRK2 (0.50) | ARTBXA2RLRRK2EPAS1SLC6A4 | |
| SCHEMBL13997552 | 0.78 | HTR2A (0.50) | ARLRRK2SCN8ASCN10AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |