⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19127443 | 0.69 | — | — | |
| SCHEMBL3517566 | 0.69 | — | — | |
| SCHEMBL2358531 | 0.69 | — | — | |
| SCHEMBL9233507 | 0.69 | — | — | |
| SCHEMBL30167959 | 0.69 | — | — | |
| SCHEMBL3416266 | 0.68 | — | — | |
| SCHEMBL11237771 | 0.67 | — | — | |
| SCHEMBL9066164 | 0.67 | — | — | |
| SCHEMBL3432497 | 0.67 | — | — | |
| SCHEMBL18804229 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4807884-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| US-7750040-B2 | G protein-coupled receptor S1P1/EDG1 agonists; low dosage, long lasting immunosuppressive effect; such as 1,1,2-trimethyl-1,1a,5,5a-tetrahydro-3-thia-cyclopropa[a]pentalene-4-carboxylic acid 2,4-dimethoxy-benzylamide | ACTELION PHARMACEUTICALS LTD. (CH) | 2010-07-06 | — | — | US | claimed |
| EP-1805163-B1 | 1,1A,5,5A-TETRAHYDRO-3-THIA-CYCLOPROPA[A]PENTALENES: TRICYCLIC THIOPHENE DERIVATIVES AS S1P1/EDG1 RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-01 | — | — | EP | claimed |
| US-20080064740-A1 | Novel Thiophene Derivatives | ACTELION PHARMACEUTICALS, LTD. (CH) | 2008-03-13 | — | — | US | claimed |
| EP-1805163-A2 | 1,1A,5,5A-TETRAHYDRO-3-THIA-CYCLOPROPA¬A|PENTALENES: TRICYCLIC THIOPHENE DERIVATIVES AS S1P1/EDG1 RECEPTOR AGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2007-07-11 | — | — | EP | claimed |
| WO-2006010544-A2 | 1, 1A, 5, 5A-TETRAHYDRO-3-THIA-CYCLOPROPA’A! PENTALENES: TRICYCLIC THIOPHENE DERIVATIVES AS S1P1/EDG1 RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-02-02 | — | — | WO | claimed |
| US-20030143758-A1 | Insoluble carrier particle nephelometric immunoassay reagent | SRL, INC. (JP) | 2003-07-31 | — | — | US | claimed |
| EP-1298438-A1 | INSOLUBLE CARRIER PARTICLE NEPHELOMETRIC IMMUNOASSAY REAGENT | KYOWA MEDEX CO., LTD. (JP) | 2003-04-02 | — | — | EP | claimed |
| JP-6256363-A | — | — | None | — | — | JP | disclosed |
| JP-2164861-A | — | — | None | — | — | JP | disclosed |
| JP-7238076-A | — | — | None | — | — | JP | disclosed |
| US-11925179-B2 | Glyphosate formulations containing amidoalkylamine surfactants | MONSANTO TECHNOLOGY LLC (US) | 2024-03-12 | — | — | US | disclosed |
| CN-114364257-B | Herbicidal mixtures containing amine salts of acid herbicides | 孟山都技术公司 | 2024-02-23 | — | — | CN | disclosed |
| US-11864558-B2 | Herbicidal compositions containing N-phosphonomethyl glycine and an auxin herbicide | MONSANTO TECHNOLOGY LLC (US) | 2024-01-09 | — | — | US | disclosed |
| WO-2001014334-A1 | FLUORENONE COMPOUNDS WITH MODIFIED 7-POSITION SUBSTITUENTS FOR TREATING AND PREVENTING BRAIN AND SPINAL INJURY | QUESTCOR PHARMACEUTICALS, INC. (US) | 2001-03-01 | — | — | WO | disclosed |
| US-5523433-A | Process for the preparation of diethyl ester dimethyl ammonium chloride | WITCO CORPORATION (US) | 1996-06-04 | — | — | US | disclosed |
| JP-H07238076-A | PRODUCTION OF OPTICALLY ACTIVE VINYLDIHYDROFURAN COMPOUND | SUMITOMO CHEM CO LTD | 1995-09-12 | — | — | JP | disclosed |
| JP-H06256363-A | PRODUCTION OF OPTICALLY ACTIVE SILYL COMPOUND | SUMITOMO CHEM CO LTD | 1994-09-13 | — | — | JP | disclosed |
| JP-H02164861-A | OPTICAL ACTIVE CYCLOPENTANE DERIVATIVE AND ITS PRODUCTION | SUMITOMO CHEM CO LTD | 1990-06-25 | — | — | JP | disclosed |
| US-4405725-A | Foamed polyisocyanurates | MOBAY CHEMICAL CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |