Tetrahydrofuran

Tetrahydrofuran

SCHEMBL4377160

C1CCOC1.C1CCOC1.C1CCOC1.C1CCOC1.C1CCOC1.C1CCOC1.C1CCOC1.C1CCOC1.C1CCOC1.C1CCOC1.C1CCOC1.C1CCOC1.C1CCOC1.C1CCOC1.CCCCCCC1CCCO1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.69
ALDH1A1 P00352 2/20 0.52
CYP1A2 P05177 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
USP2 O75604 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TLR7 Q9NYK1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL6857200 1.00 EPHX1 (0.69) EPHX1ALDH1A1CYP1A2TDP1TP53
Tetrahydrofuran SCHEMBL29168530 0.93 EPHX1 (0.57) EPHX1ALDH1A1CYP1A2TDP1TP53
SCHEMBL13423666 0.93 EPHX1 (0.80) EPHX1ALDH1A1CYP1A2TDP1TP53
SCHEMBL20440346 0.93 EPHX1 (0.80) EPHX1ALDH1A1CYP1A2TDP1TP53
SCHEMBL409221 0.93 EPHX1 (0.80) EPHX1ALDH1A1CYP1A2TDP1TP53
SCHEMBL5515259 0.93 EPHX1 (0.80) EPHX1ALDH1A1CYP1A2TDP1TP53
SCHEMBL4626384 0.93 EPHX1 (0.80) EPHX1ALDH1A1CYP1A2TDP1TP53
SCHEMBL18825665 0.93 EPHX1 (0.80) EPHX1ALDH1A1CYP1A2TDP1TP53
SCHEMBL538474 0.93 EPHX1 (0.80) EPHX1ALDH1A1CYP1A2TDP1TP53
SCHEMBL23961183 0.91 EPHX1 (0.77) EPHX1ALDH1A1CYP1A2TDP1TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2103445-B1 Heat resistance improver and reversible thermosensitive recording medium RICOH CO LTD (JP) 2015-05-06 EP disclosed
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
EP-2103445-A1 Heat resistance improver and reversible thermosensitive recording medium Ricoh Company, Ltd. (JP) 2009-09-23 EP disclosed