SCHEMBL437720

SCHEMBL437720

CCCc1cc(N)c2cc(C(F)(F)F)ccc2n1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 19/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439523 0.89 MCHR1 (0.57) MCHR1
SCHEMBL6310770 0.83 MCHR1 (1.00) MCHR1
SCHEMBL437488 0.81 MCHR1 (0.58) MCHR1
SCHEMBL6310467 0.81 MCHR1 (1.00) MCHR1
SCHEMBL4264863 0.80 MCHR1 (0.56) MCHR1
SCHEMBL6202397 0.80 MCHR1 (1.00) MCHR1
SCHEMBL436437 0.80 MCHR1 (0.51) MCHR1
SCHEMBL6199666 0.79 MCHR1 (1.00) MCHR1
SCHEMBL6199667 0.79 MCHR1 (1.00) MCHR1
SCHEMBL6316880 0.79 MCHR1 (1.00) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120065166-A1 Bone Modulators And Methods Therewith ESPINA VIRGINIA (US) 2012-03-15 US disclosed