Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4377512 | 0.80 | HRH3 (0.76) | HRH3POLBDRD2DRD4DRD3 | |
| SCHEMBL4377725 | 0.80 | HRH3 (0.97) | HRH3POLBDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL4378983 | 0.79 | HRH3 (1.00) | HRH3POLBDRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL4381928 | 0.79 | HRH3 (0.78) | HRH3POLBDRD2DRD4DRD3 | |
| SCHEMBL4378327 | 0.79 | HRH3 (1.00) | HRH3 | |
| SCHEMBL4379195 | 0.79 | SMN1; SMN2 (0.66) | HRH3HTTSMN1; SMN2 | |
| SCHEMBL4386127 | 0.79 | HRH3 (1.00) | HRH3POLBHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4376343 | 0.78 | HRH3 (1.00) | HRH3 | |
| Hydrochloric Acid SCHEMBL4381864 | 0.78 | HRH3 (1.00) | HRH3POLBHTTSMN1; SMN2 | |
| SCHEMBL4379229 | 0.71 | HRH3 (0.98) | HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421071-B1 | SUBSTITUTED PIPERAZINE AND DIAZEPANE DERIVAIVES AS HISTAMINE H3 RECEPTOR MODULATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2009-11-18 | — | — | EP | claimed |