Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 18/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227213 | 0.92 | UTS2R (0.51) | UTS2RROCK2ROCK1 | |
| SCHEMBL3227897 | 0.91 | UTS2R (0.52) | UTS2RROCK2ROCK1 | |
| SCHEMBL3233601 | 0.90 | UTS2R (0.42) | UTS2RROCK2ROCK1 | |
| SCHEMBL3223876 | 0.89 | UTS2R (0.44) | UTS2RROCK2ROCK1 | |
| SCHEMBL3222714 | 0.88 | UTS2R (0.39) | UTS2RROCK2ROCK1 | |
| SCHEMBL3234631 | 0.88 | NAMPT (0.42) | UTS2RROCK2ROCK1 | |
| SCHEMBL3234013 | 0.88 | UTS2R (0.43) | UTS2RROCK2ROCK1 | |
| SCHEMBL3226314 | 0.87 | UTS2R (0.42) | UTS2RROCK2ROCK1 | |
| SCHEMBL3230143 | 0.87 | UTS2R (0.40) | UTS2RROCK2ROCK1 | |
| SCHEMBL3227966 | 0.87 | UTS2R (0.42) | UTS2RROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2135620-A1 | OCULAR HYPOTENSIVE AGENT COMPRISING COMPOUND CAPABLE OF INHIBITING HISTONE DEACETYLASE AS ACTIVE INGREDIENT | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-23 | — | — | EP | disclosed |