⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4378579 | 0.83 | — | — | |
| SCHEMBL12812094 | 0.77 | — | — | |
| SCHEMBL4382489 | 0.75 | — | — | |
| SCHEMBL4392998 | 0.73 | CNR1 (0.31) | — | |
| SCHEMBL4386644 | 0.69 | — | — | |
| SCHEMBL4378054 | 0.69 | — | — | |
| SCHEMBL10153237 | 0.69 | — | — | |
| SCHEMBL4387548 | 0.68 | HRH3 (0.36) | — | |
| SCHEMBL2766931 | 0.68 | — | — | |
| SCHEMBL15346124 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |