Dioxane

Dioxane

SCHEMBL4378083

C1COCCO1.c1ccccc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.67
LMNA P02545 3/20 0.45
CRHBP P24387 2/20 0.44
CRHR2 Q13324 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HTT P42858 1/20 0.44
ALDH1A1 P00352 1/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 2/20 0.36
TP53 P04637 1/20 0.33
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
CYP2C9 P11712 1/20 0.31
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL88326 0.94
SCHEMBL78595 0.82 TTR (1.00) TTRLMNACRHBPCRHR2SMN1; SMN2
SCHEMBL6057268 0.82 TTR (1.00) TTRLMNACRHBPCRHR2SMN1; SMN2
SCHEMBL3137720 0.82 TTR (1.00) TTRLMNACRHBPCRHR2SMN1; SMN2
Dioxane SCHEMBL9836999 0.82
SCHEMBL1119 0.82 TTR (1.00) TTRLMNACRHBPCRHR2SMN1; SMN2
Dioxane SCHEMBL3631647 0.82 TTR (1.00) TTRLMNACRHBPCRHR2SMN1; SMN2
SCHEMBL11207601 0.82 TTR (1.00) TTRLMNACRHBPCRHR2SMN1; SMN2
SCHEMBL3137753 0.82 TTR (1.00) TTRLMNACRHBPCRHR2SMN1; SMN2
SCHEMBL16041435 0.82 TTR (1.00) TTRLMNACRHBPCRHR2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106110402-A Organization engineering skin that Sodium Alginate Hydrogel Films support builds and preparation method thereof 朱家源 2016-11-16 CN claimed
CN-102199306-A Membrane for sealing bag on inner wall of large airplane and surface treatment method thereof SUZHOU SIDIKE STICKINESS ELECTRON STUFF CO LTD 2011-09-28 CN claimed
CN-101274037-B Detection method of composition for curing skin pruritus BEIJING ASIA EAST BIO PHARM CO 2011-08-17 CN claimed
US-4413145-A Process for the synthesis of 3-keto-cyclopentene-5-oxy derivatives having insecticide activity CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1983-11-01 US claimed
US-11779883-B2 Water purification systems and methods having pressurized draw stream PORIFERA, INC. (US) 2023-10-10 US disclosed
CN-116194443-A Co-production of monomers, including at least one biobased monomer 阿彻丹尼尔斯米德兰公司 2023-05-30 CN disclosed
CN-115044044-B Sulfonic group modified silicone oil and preparation method and application thereof 枣阳市华威硅氟材料有限公司 2023-04-14 CN disclosed
CN-110981906-B Synthetic method of isomeric dodecyl alcohol polyoxyethylene ether phosphate ester 浙江皇马科技股份有限公司 2022-08-09 CN disclosed
US-20220054981-A1 WATER PURIFICATION SYSTEMS AND METHODS HAVING PRESSURIZED DRAW STREAM PORIFERA, INC. (US) 2022-02-24 US disclosed
US-11173452-B2 Water purification systems and methods having pressurized draw stream PORIFERA, INC. (US) 2021-11-16 US disclosed
US-10822527-B2 Thermosetting adhesive composition, thermosetting adhesive film, and composite film TOMOEGAWA CO., LTD. (JP) 2020-11-03 US disclosed
CN-107057001-B Rosin-based comb-shaped high-molecular surfactant and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2020-04-21 CN disclosed
US-4066675-A PSORIASIS, THROMBOSIS MERCK & CO., INC. (US) 1978-01-03 US disclosed
US-4049811-A MICROBIOCIDES BOEHRINGER MANNHEIM G.M.B.H. (DT) 1977-09-20 US disclosed
US-4041047-A ANTIASTHMATICS CIBA-GEIGY CORPORATION (US) 1977-08-09 US disclosed
US-4018802-A SKIN DISEASES, GROWTH HORMONE STIMULANTS, THROMBUS PREVENTION, IMMUNOLOGY MERCK & CO., INC. (US) 1977-04-19 US disclosed
US-3987029-A Antibacterial antibiotics AM31α, AM31β and AM31γ AMERICAN CYANAMID COMPANY (US) 1976-10-19 US disclosed
US-3966743-A ANTIMICROBIAL BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-06-29 US disclosed
US-3957766-A BACTERIOSTATS, BACTERICIDES BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-05-18 US disclosed
US-3931297-A 10-Hydroxy PGC compounds SYNTEX (U.S.A.) INC. (US) 1976-01-06 US disclosed