SCHEMBL4378090

SCHEMBL4378090

[CH2]C1C=CC(Cl)(Cl)C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15899268 0.68
SCHEMBL4097032 0.67
SCHEMBL8812904 0.67
SCHEMBL2698202 0.57
SCHEMBL27763292 0.55
SCHEMBL27692977 0.55
SCHEMBL31611884 0.55
SCHEMBL27560384 0.55
SCHEMBL28129979 0.55
SCHEMBL6502350 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150366643-A1 TOOTH VENEER ELEMENT, AND METHOD FOR THE USE AND PRODUCTION THEREOF COLTÈNE/WHALEDENT AG (CH) 2015-12-24 US disclosed
WO-2013105049-A1 FLUOROPHOSPHONYL COMPOUNDS, COMPOSITION CONTAINING SAME AND USE THEREOF FOR RESTORING TEETH CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-07-18 WO disclosed
US-20090297458-A1 Dental materials equipped with active anti-plaque substance(s) HERAEUS KULZER GMBH (DE) 2009-12-03 US disclosed
US-7425587-B2 Flowable underfilling material HERAECUS KULZER GMBH (DE) 2008-09-16 US disclosed
US-20050215659-A1 Dispersions of nanoscale, non-agglomerated particles for use in dental materials HERAEUS KULZER GMBH (DE) 2005-09-29 US disclosed
US-20050192375-A1 Easily visible and distinguishable from tooth substance; free radical polymerizable monomers, photoinitiator and white pigment; cavity restoration HERAEUS KULZER GMBH (DE) 2005-09-01 US disclosed
US-6900251-B2 Dental materials based on acrylic-ester phosphonic acids IVOCLAR VIVADENT AG (LI) 2005-05-31 US disclosed
US-20040077754-A1 Dental materials based on acrylic-ester phosphonic acids IVOCLAR VIVADENT AG (LI) 2004-04-22 US disclosed