Deoxyfuconojirimycin

Deoxyfuconojirimycin

SCHEMBL4378188

C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FUCA1 P04066 5/20 1.00
▸ FUCA2 Q9BTY2 1/20 1.00
▸ GLB1 P16278 1/20 0.58
▸ GBA1 P04062 5/20 0.54
▸ GLA P06280 1/20 0.48
▸ GAA P10253 1/20 0.48
▸ GANAB Q14697 1/20 0.46
▸ MAN2B1 O00754 1/20 0.46
▸ MAN2B2 Q9Y2E5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxyfuconojirimycin SCHEMBL15686574 1.00 FUCA1 (1.00) FUCA1FUCA2GLB1GBA1GLA
Deoxyfuconojirimycin SCHEMBL12581516 1.00 FUCA1 (1.00) FUCA1FUCA2GLB1GBA1GLA
Deoxyfuconojirimycin SCHEMBL2436650 1.00 FUCA1 (1.00) FUCA1FUCA2GLB1GBA1GLA
Deoxyfuconojirimycin SCHEMBL9999893 1.00 FUCA1 (1.00) FUCA1FUCA2GLB1GBA1GLA
Deoxyfuconojirimycin SCHEMBL15691930 1.00 FUCA1 (1.00) FUCA1FUCA2GLB1GBA1GLA
Deoxyfuconojirimycin SCHEMBL13328524 1.00 FUCA1 (1.00) FUCA1FUCA2GLB1GBA1GLA
Deoxyfuconojirimycin SCHEMBL13876087 1.00 FUCA1 (1.00) FUCA1FUCA2GLB1GBA1GLA
Deoxyfuconojirimycin SCHEMBL1867289 1.00 FUCA1 (1.00) FUCA1FUCA2GLB1GBA1GLA
Deoxyfuconojirimycin SCHEMBL13876082 1.00 FUCA1 (1.00) FUCA1FUCA2GLB1GBA1GLA
Deoxyfuconojirimycin SCHEMBL2435560 1.00 FUCA1 (1.00) FUCA1FUCA2GLB1GBA1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2196758-A — — None — — JP disclosed
US-8242136-B2 Use of glucosidase inhibitors for therapy of mucovisidosis CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2012-08-14 — — US disclosed
US-20110269795-A1 USE OF GLUCOSIDASE INHIBITORS FOR THERAPY OF MUCOVISIDOSIS UNIVERSITE DE POITIERS (FR) 2011-11-03 — — US disclosed
US-7973054-B2 Use of glucosidase inhibitors for therapy of mucovisidosis CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2011-07-05 — — US disclosed
EP-1411952-B1 USE OF AT LEAST ONE GLYCOINHIBITOR SUBSTANCE AGAINST INFECTIOUS DISEASES GLYKOS FINLAND OY (FI) 2009-04-22 — — EP disclosed
US-20070213357-A1 Use of Glucosidase Inhibitors for Therapy of Mucovisidosis CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2007-09-13 — — US disclosed
US-20040176320-A1 Use of at least one glycoinhibitor substance BIOTIE THERAPIES COPR. (FI) 2004-09-09 — — US disclosed
EP-1411952-A1 USE OF AT LEAST ONE GLYCOINHIBITOR SUBSTANCE Carbion OY (FI) 2004-04-28 — — EP disclosed
WO-2003002127-A1 USE OF AT LEAST ONE GLYCOINHIBITOR SUBSTANCE GLYKOS FINLAND OY (FI) 2003-01-09 — — WO disclosed
EP-0406211-B1 Fucosidase inhibitors MONSANTO CO (US) 1994-03-30 — — EP disclosed
EP-0409812-A2 Fucosidase inhibitor MONSANTO COMPANY (US) 1991-01-23 — — EP disclosed
EP-0406211-A2 Fucosidase inhibitors MONSANTO COMPANY (US) 1991-01-02 — — EP disclosed
JP-H02196758-A SYNTHESIS OF N-SUBSTITUTED 1,5-DIDEOXY-1,5-IMONO-L-FUCITOL DERIVATIVE G D SEARLE & CO 1990-08-03 — — JP disclosed
EP-0363344-A1 Synthesis of N-substituted 1,5-dideoxy-1,5-imino-L-fucitol derivatives G.D. SEARLE & COMPANY (US) 1990-04-11 — — EP disclosed
EP-0363344-A1 Synthesis of N-substituted 1,5-dideoxy-1,5-imino-L-fucitol derivatives G.D. SEARLE & COMPANY (US) 1990-04-11 — — EP disclosed
EP-0363344-A1 Synthesis of N-substituted 1,5-dideoxy-1,5-imino-L-fucitol derivatives G.D. SEARLE & COMPANY (US) 1990-04-11 — — EP disclosed
US-4910310-A Esterification of 2,3-O-isopropylidene-D-lyxono-1,4-lactone G. D. SEARLE & CO. (US) 1990-03-20 — — US disclosed
US-4910310-A Esterification of 2,3-O-isopropylidene-D-lyxono-1,4-lactone G. D. SEARLE & CO. (US) 1990-03-20 — — US disclosed
US-4910310-A Esterification of 2,3-O-isopropylidene-D-lyxono-1,4-lactone G. D. SEARLE & CO. (US) 1990-03-20 — — US disclosed
EP-0322395-A1 Heterocyclic compounds for inhibiting virus Monsanto Company (US) 1989-06-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269795-A1 USE OF GLUCOSIDASE INHIBITORS FOR THERAPY OF MUCOVISIDOSIS MAN2B1, GAA, MAN2A1 FUCA1 13/4885FUCA2 32/4885GLB1 61/4885
US-20070213357-A1 Use of Glucosidase Inhibitors for Therapy of Mucovisidosis MAN2B1, GAA, MAN2A1 FUCA1 12/4885FUCA2 35/4885GLB1 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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