Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159716 | 0.89 | — | — | |
| SCHEMBL6359432 | 0.86 | — | — | |
| Alcohol SCHEMBL27958122 | 0.81 | TSHR (0.38) | TSHRTDP1ALDH1A1 | |
| SCHEMBL2329675 | 0.80 | — | — | |
| SCHEMBL4529846 | 0.78 | TSHR (0.43) | TSHRTDP1ALDH1A1 | |
| SCHEMBL4535326 | 0.78 | TSHR (0.43) | TSHRTDP1ALDH1A1 | |
| SCHEMBL5575657 | 0.78 | TSHR (0.43) | TSHRTDP1ALDH1A1 | |
| SCHEMBL4534717 | 0.78 | TSHR (0.43) | TSHRTDP1ALDH1A1 | |
| SCHEMBL8756007 | 0.78 | TSHR (0.43) | TSHRTDP1ALDH1A1 | |
| SCHEMBL4528652 | 0.78 | TSHR (0.43) | TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1637534-B1 | Process for preparing organodiakylalkoxysilanes | RHODIA CHIMIE SA (FR) | 2009-11-25 | — | — | EP | disclosed |
| CN-101186618-A | Process for preparing organodiakylalkoxysilanes | RHONE POULENC CHIMIE (FR) | 2008-05-28 | — | — | CN | disclosed |
| CN-100355765-C | Process for preparing organodialkylalkoxysilanes | RHONE POULENC CHIMIE (FR) | 2007-12-19 | — | — | CN | disclosed |
| EP-1515977-B1 | METHOD OF PREPARING ORGANO DIALKYLALKOXYSILANE | RHODIA CHIMIE SA (FR) | 2007-08-29 | — | — | EP | disclosed |
| EP-1637534-A1 | Process for preparing organodiakylalkoxysilanes | RHODIA CHIMIE (FR) | 2006-03-22 | — | — | EP | disclosed |
| EP-1515977-A1 | METHOD OF PREPARING ORGANO DIALKYLALKOXYSILANE | Rhodia Chimie SA (FR) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004000852-A1 | METHOD OF PREPARING ORGANO DIALKYLALKOXYSILANE | RHODIA CHIMIE SA (FR) | 2003-12-31 | — | — | WO | disclosed |