Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169260 | 0.78 | MEN1 (0.40) | MEN1KMT2AIDO1CYP3A4HTR2A | |
| SCHEMBL16503516 | 0.77 | TSHR (0.40) | MEN1KMT2ABACE1CYP1A2 | |
| SCHEMBL28410304 | 0.76 | CYP1A2 (0.39) | MEN1KMT2AIDO1BACE1CYP3A4 | |
| SCHEMBL16503520 | 0.75 | KMT2A (0.39) | MEN1KMT2ABACE1CYP1A2 | |
| SCHEMBL7724629 | 0.73 | CYP1A2 (0.44) | MEN1KMT2ABACE1CYP1A2 | |
| SCHEMBL7772540 | 0.73 | MEN1 (0.36) | MEN1KMT2AIDO1BACE1CYP1A2 | |
| SCHEMBL7772537 | 0.73 | MEN1 (0.36) | MEN1KMT2AIDO1BACE1CYP1A2 | |
| SCHEMBL11899615 | 0.73 | CYP3A4 (0.38) | MEN1KMT2ABACE1CYP3A4CYP1A2 | |
| SCHEMBL11899259 | 0.73 | MEN1 (0.36) | MEN1KMT2ABACE1CYP3A4CYP1A2 | |
| SCHEMBL7724626 | 0.73 | CYP1A2 (0.44) | MEN1KMT2ABACE1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101711-B2 | Process to modify polymeric materials and resulting compositions | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-24 | — | — | US | disclosed |