Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 7/20 | 0.39 |
| ▸ | CNR1 | P21554 | 6/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14261070 | 0.87 | CNR2 (0.43) | PARGCNR1CNR2NPC1OPRM1 | |
| SCHEMBL3918409 | 0.85 | CNR2 (0.43) | CNR1CNR2NPC1OPRM1OPRL1 | |
| SCHEMBL3921045 | 0.79 | CNR2 (0.42) | PARGCNR1CNR2NPC1PLA2G2A | |
| SCHEMBL4277365 | 0.79 | CNR1 (0.46) | PARGCNR1CNR2NPC1PLA2G2A | |
| SCHEMBL4385172 | 0.78 | CNR2 (0.59) | CNR1CNR2NPC1PLA2G2AOPRM1 | |
| SCHEMBL14260974 | 0.78 | CNR2 (0.59) | CNR1CNR2NPC1PLA2G2AOPRM1 | |
| SCHEMBL3916514 | 0.77 | CNR2 (0.41) | CNR1CNR2NPC1PLA2G2AOPRM1 | |
| SCHEMBL3925636 | 0.77 | CNR2 (0.41) | CNR1CNR2NPC1PLA2G2AOPRM1 | |
| SCHEMBL3920939 | 0.75 | CNR2 (0.44) | CNR1CNR2NPC1 | |
| SCHEMBL3927215 | 0.74 | CNR2 (0.59) | PARGCNR1CNR2NPC1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298811-A1 | BENZIMIDAZOLONE DERIVATIVES | PFIZER INC | 2009-12-03 | — | — | US | disclosed |
| WO-2008032164-A2 | BENZIMIDAZOLONE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298811-A1 | BENZIMIDAZOLONE DERIVATIVES | TRPV1, CNR1, CNR2 | PARG 4724/4885CNR1 2/4885CNR2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.