Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GABRR1 | P24046 | 5/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.37 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899221 | 0.86 | GABRR1 (0.44) | TP53GABRR1SLC7A5GABRR2BLM | |
| Alanine SCHEMBL28681591 | 0.84 | GABRR1 (0.42) | GABRR1SLC7A5GRIK1GRIA2GRIA4 | |
| Lactic Acid SCHEMBL1025752 | 0.82 | TP53 (0.55) | TP53GABRR1SLC7A5GABRR2BLM | |
| Lactic Acid SCHEMBL28777167 | 0.81 | TP53 (0.61) | TP53GABRR1SLC7A5TSHRTDP1 | |
| Lactic Acid SCHEMBL31326881 | 0.80 | TP53 (0.69) | TP53GABRR1SLC7A5LMNASLC1A3 | |
| Lactic Acid SCHEMBL27979213 | 0.80 | TP53 (0.69) | TP53GABRR1SLC7A5LMNASLC1A3 | |
| Lactic Acid SCHEMBL7195657 | 0.80 | — | — | |
| Lactic Acid SCHEMBL7803238 | 0.78 | TP53 (0.65) | TP53GABRR1SLC7A5LMNASLC1A3 | |
| Lactic Acid SCHEMBL3253029 | 0.78 | TP53 (0.65) | TP53GABRR1SLC7A5LMNA | |
| Lactic Acid SCHEMBL10934337 | 0.78 | TP53 (0.65) | TP53GABRR1SLC7A5LMNASLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116997449-A | Enhanced wood preservative containing zinc and boron | 阿萨达有限责任公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-113977723-A | Wood preservative composition | 奥麟木材保护有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-110587753-A | Wood preservative composition | 奥麟木材保护有限公司 | 2019-12-20 | — | — | CN | disclosed |
| WO-2009133374-A2 | ANTISAPSTAIN COMPOSITIONS COMPRISING A HALOALKYNYL COMPOUND, AN AZOLE AND AN UNSATURATED ACID | ARCH TIMBER PROTECTION LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |
| EP-1135239-A1 | WOOD PRESERVATIVE FORMULATIONS | HICKSON INTERNATIONAL PLC (GB) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000032371-A1 | WOOD PRESERVATIVE FORMULATIONS | HICKSON INTERNATIONAL PLC (GB) | 2000-06-08 | — | — | WO | disclosed |