SCHEMBL438029

SCHEMBL438029

[C]1NC2C=CC=CC2O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL299961 0.64
SCHEMBL19743847 0.60
SCHEMBL152393 0.60
SCHEMBL13679653 0.60
SCHEMBL16516938 0.56
SCHEMBL17104869 0.56
SCHEMBL707812 0.54
SCHEMBL14138851 0.54
SCHEMBL17104842 0.54
SCHEMBL701713 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192617-A1 AZABICYCLIC(THIO)AMIDES AS FUNGICIDAL COMPOUNDS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2023-06-22 US claimed
EP-4153566-A1 AZABICYCLIC(THIO)AMIDES AS FUNGICIDAL COMPOUNDS Bayer CropScience Aktiengesellschaft (DE) 2023-03-29 EP claimed
CN-115803317-A Azabicyclo (thio) amides as fungicidal compounds 拜耳作物科学股份公司 2023-03-14 CN claimed
US-20220396571-A1 SPIROPIPERIDINE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS MERCK SHARP & DOHME CORP. (US) 2022-12-15 US claimed
WO-2021233861-A1 AZABICYCLIC(THIO)AMIDES AS FUNGICIDAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2021-11-25 WO claimed
US-10870630-B2 Substituted bicyclic heteroaryl allosteric modulators of nicotinic acetylcholine receptors MERCK SHARP & DOHME CORP. 2020-12-22 US claimed
US-10738056-B2 Pyrazolopyrimidinone compounds and uses thereof ADURO BIOTECH INC. (US) 2020-08-11 US claimed
EP-3681888-A1 PYRAZOLOPYRIMIDINONE COMPOUNDS AND USES THEREOF Aduro Biotech, Inc. (US) 2020-07-22 EP claimed
WO-2020123422-A1 IMIDAZOPYRIDAZINONE COMPOUNDS AND USES THEREOF Aduro Biotech, Inc. (US) 2020-06-18 WO claimed
US-20200181153-A1 IMIDAZOPYRIDAZINONE COMPOUNDS AND USES THEREOF CHINOOK THERAPEUTICS, INC. 2020-06-11 US claimed
WO-2010001220-A1 NEW 1,2,4-TRIAZINE DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF MUTABILIS SA (FR) 2010-01-07 WO claimed
EP-2141164-A1 New 1,2,4-triazine derivatives and biological applications thereof Mutabilis (FR) 2010-01-06 EP claimed
EP-2081905-A2 SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR Boehringer Ingelheim International GmbH (DE) 2009-07-29 EP claimed
EP-2074084-A1 COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR Boehringer Ingelheim International GmbH (DE) 2009-07-01 EP claimed
WO-2008064054-A2 COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-05-29 WO claimed
US-20080081822-A1 N-(5-tert-Butyl-isoxazol-3-yl)-2-cyclohexanesulfonyl-2-methyl-propionamide; cannabinoid receptor agonist, antagonist; analgesic, antiinflammatory and antitumor agent; neuropatic pain BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-04-03 US claimed
WO-2008039645-A1 COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-04-03 WO claimed
US-20080039464-A1 Compounds Which Modulate The CB2 Receptor BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-02-14 US claimed
WO-2008014199-A2 SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-01-31 WO claimed
US-5225589-A Organic compositions and their manufacture EASTMAN KODAK COMPANY (US) 1993-07-06 US claimed