SCHEMBL4380482

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2626366	0.83	SCN9A (0.41)	MAPTF10GRM5TP53LMNA
	SCHEMBL14218140	0.82	MAPT (0.54)	MAPTLMNAKDM4ENPC1RAB9A
	SCHEMBL4380469	0.78	MAPT (0.50)	MAPTLMNAATMNPC1RAB9A
	SCHEMBL4380711	0.78	MAPT (0.50)	MAPTKDM4E
	SCHEMBL2834155	0.76	MAPT (0.50)	MAPTF10TP53
	Tianafac SCHEMBL2109723	0.72	MAPT (0.67)	MAPTROCK1KDM4EMEN1KMT2A
	SCHEMBL1653448	0.72	F10 (0.54)	MAPTF10
	SCHEMBL14817940	0.69	GFER (0.68)	MAPTLMNAKDM4EPOLBGFER
	SCHEMBL6600563	0.68	MAPT (0.62)	MAPTF10LMNA
	SCHEMBL4377859	0.68	CYP1A2 (0.71)	MAPTF10GRM5TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.