⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083117 | 1.00 | — | — | |
| SCHEMBL8638564 | 0.97 | TSHR (0.44) | — | |
| SCHEMBL7863914 | 0.97 | TSHR (0.44) | — | |
| SCHEMBL9428891 | 0.97 | TSHR (0.44) | — | |
| SCHEMBL9427759 | 0.97 | TSHR (0.44) | — | |
| SCHEMBL4312065 | 0.97 | — | — | |
| SCHEMBL9510813 | 0.97 | TSHR (0.44) | — | |
| SCHEMBL7866734 | 0.97 | TSHR (0.44) | — | |
| SCHEMBL237153 | 0.97 | TSHR (0.44) | — | |
| SCHEMBL7869268 | 0.97 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108242566-A | Electrolyte solution and secondary battery | 宁德时代新能源科技股份有限公司 | 2018-07-03 | — | — | CN | claimed |
| US-4772309-A | 5-acylamino-pyrazoles, composition containing them, and herbicidal and plant growth regulating method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | claimed |
| EP-4281072-A1 | FERROPORTIN-INHIBITORS FOR THE USE IN THE TREATMENT OF MYELODYSPLASTIC SYNDROMES (MDS) | VIFOR (INTERNATIONAL) AG (CH) | 2023-11-29 | — | — | EP | disclosed |
| CN-116710091-A | Membrane iron transporter inhibitors for the treatment of myelodysplastic syndrome (MDS) | 威佛（国际）股份公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-110785417-B | Membrane iron transporter inhibitor salts | 威佛（国际）股份公司 | 2023-05-23 | — | — | CN | disclosed |
| US-20220273634-A1 | Ferroportin-Inhibitors For The Use In The Treatment Of Transfusion-Dependent Beta-Thalassemia (TDT) | VIFOR (INTERNATIONAL) AG (CH) | 2022-09-01 | — | — | US | disclosed |
| CN-114765955-A | Methods and compositions for treating sickle cell disease with an iron transporter inhibitor (VIT-2763) | 威佛（国际）股份公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-114668761-A | Novel ferroportin inhibitors | 威佛（国际）股份公司 | 2022-06-28 | — | — | CN | disclosed |
| EP-3999060-A1 | FERROPORTIN-INHIBITORS FOR THE USE IN THE PREVENTION AND TREATMENT OF KIDNEY INJURIES | VIFOR (INTERNATIONAL) AG (CH) | 2022-05-25 | — | — | EP | disclosed |
| EP-3999059-A1 | FERROPORTIN-INHIBITORS FOR THE USE IN THE TREATMENT OF TRANSFUSION-DEPENDENT BETA-THALASSEMIA (TDT) | VIFOR (INTERNATIONAL) AG (CH) | 2022-05-25 | — | — | EP | disclosed |
| CN-108290878-B | Novel ferroportin inhibitors | 威佛（国际）股份公司 | 2022-04-26 | — | — | CN | disclosed |
| US-4481368-A | Process for preparing α-keto-carboxylic acids from acyl halides | ETHYL CORPORATION (US) | 1984-11-06 | — | — | US | disclosed |
| US-4481369-A | VIA TRICARBONYL(TRIPHENYLPOSPHINE) COBALTATE | ETHYL CORPORATION (US) | 1984-11-06 | — | — | US | disclosed |
| US-4082517-A | CYCLOPENTADIENYL MANGANESE ANTIKNOCK | ETHYL CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |
| US-RE29488-E | CYCLOPENTADIENYL MANGANESE TRICARBONYL, CARBOXYMETHOXY-SUCCINIC ACIDS | ETHYL CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |
| US-4052171-A | FUEL COMPOSITIONS AND ADDITIVE MIXTURES CONTAINING METHANETRICARBOXYLATES FOR REDUCING EXHAUST GAS CATALYST PLUGGING | ETHYL CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |
| US-4005992-A | CYCLOPENTADIENYL MAGNESIUM TRICARBONYL, OXYMETHYLENEMALONIC ACIDS OR ESTERS | ETHYL CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-4005993-A | CYCLOPENTADIENYL MANGANESE TRICARBONYL, OXYALKYL-MALONIC ACIDS OR ESTERS | ETHYL CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-3958955-A | CYCLOPENTADIENYL MANGANESE TRICARBONYL ANTIKNOCK | ETHYL CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |
| US-3950145-A | ANTIKNOCK | ETHYL CORPORATION (US) | 1976-04-13 | — | — | US | disclosed |