Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31034848 | 0.89 | TSHR (0.52) | NNMTPARP1POLBL3MBTL1TSHR | |
| SCHEMBL12687663 | 0.77 | PARP1 (0.52) | NNMTPARP1POLBL3MBTL1TSHR | |
| SCHEMBL12160935 | 0.77 | TSHR (0.55) | TSHRCA2CA1ALDH1A1APOBEC3A | |
| SCHEMBL30505 | 0.77 | HPGD (0.46) | L3MBTL1MAPTTDP1KMT2AMAPK1 | |
| SCHEMBL4379651 | 0.75 | SMN1; SMN2 (0.52) | NNMTHDAC8 | |
| Hydrochloric Acid SCHEMBL19877380 | 0.75 | TSHR (0.52) | L3MBTL1TSHRCA2CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL152518 | 0.75 | HPGD (0.44) | L3MBTL1MAPTTDP1KMT2AMAPK1 | |
| Bromide SCHEMBL145328 | 0.75 | HPGD (0.44) | L3MBTL1MAPTTDP1KMT2AMAPK1 | |
| SCHEMBL7291835 | 0.75 | PARP1 (0.50) | NNMTPARP1POLBL3MBTL1TSHR | |
| SCHEMBL30200149 | 0.75 | USP2 (0.57) | L3MBTL1CA2CA1APOBEC3ACTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779075-A | 3- (carboxymethyl group) -8- amino -2- oxos -1,3- aza-spiro-[4.5]-decane derivative | 格吕伦塔尔有限公司 | 2018-11-09 | — | — | CN | claimed |
| EP-0049448-B1 | BETA-LACTAM ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1988-08-24 | — | — | EP | claimed |
| EP-0098433-B1 | BETA-LACTAM ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND PREPARATIONS CONTAINING THEM | BAYER AG (DE) | 1987-12-02 | — | — | EP | claimed |
| US-4626535-A | Cephalosporins | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-02 | — | — | US | claimed |
| EP-0181172-A2 | Cephalosporin antibiotics | GLAXO GROUP LIMITED (GB) | 1986-05-14 | — | — | EP | claimed |
| EP-0098433-A2 | Beta-lactam antibiotics, process for their preparation and preparations containing them | BAYER AG (DE) | 1984-01-18 | — | — | EP | claimed |
| EP-0049448-A2 | Beta-lactam antibiotics, process for their preparation and compositions containing them | BAYER AG (DE) | 1982-04-14 | — | — | EP | claimed |
| WO-2020099858-A1 | CEPHALOSPORIN CIPROFLOXACIN HYBRID COMPOUNDS | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) | 2020-05-22 | — | — | WO | disclosed |
| CN-108779075-A | 3- (carboxymethyl group) -8- amino -2- oxos -1,3- aza-spiro-[4.5]-decane derivative | 格吕伦塔尔有限公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-105849084-B | Insecticidal compounds | 先正达参股股份有限公司 | 2018-07-20 | — | — | CN | disclosed |
| CN-105873901-B | Insecticidal compounds | 先正达参股股份有限公司 | 2018-07-03 | — | — | CN | disclosed |
| US-9790252-B2 | 2-fluorinated riboses and arabinoses and methods of use and synthesis | CORNELL UNIVERSITY (US) | 2017-10-17 | — | — | US | disclosed |
| CN-105102421-B | Method for producing amides from hindered anilines containing perhaloalkyl groups | 先正达参股股份有限公司 | 2017-07-18 | — | — | CN | disclosed |
| EP-0081674-A1 | Intermediate products, process for preparing them and a process for the preparation of cephalosporins | BAYER AG (DE) | 1983-06-22 | — | — | EP | disclosed |
| US-4357331-A | 7αMethoxycephalosporin derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 1982-11-02 | — | — | US | disclosed |
| US-4338436-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338439-A | BACTERICIDAL ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4325951-A | 1-Oxadethiacephalosporin derivatives and antibacterial use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 1982-04-20 | — | — | US | disclosed |
| EP-0049448-A2 | Beta-lactam antibiotics, process for their preparation and compositions containing them | BAYER AG (DE) | 1982-04-14 | — | — | EP | disclosed |
| US-4258041-A | BROAD SPECTRUM ANTIBIOTIC EFFECTIVE AGAINST PSEUDOMONAS | GLAXO GROUP LIMITED (GB) | 1981-03-24 | — | — | US | disclosed |