Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | FABP7 | O15540 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8631515 | 0.99 | KMT2A (0.47) | KMT2AFABP5EPHX2FABP7CA1 | |
| SCHEMBL4379819 | 0.86 | KMT2A (0.48) | KMT2AFABP5EPHX2FABP7CA1 | |
| SCHEMBL18515377 | 0.86 | KMT2A (0.48) | KMT2AFABP5EPHX2FABP7CA1 | |
| Hydrochloric Acid SCHEMBL7876334 | 0.85 | KMT2A (0.47) | KMT2AFABP5EPHX2FABP7CA1 | |
| SCHEMBL3171599 | 0.82 | KMT2A (0.42) | KMT2AFABP5EPHX2FABP7CA1 | |
| SCHEMBL24620794 | 0.81 | KMT2A (0.41) | KMT2AFABP5EPHX2FABP7CA1 | |
| SCHEMBL22092037 | 0.81 | KMT2A (0.39) | KMT2AFABP5EPHX2FABP7 | |
| SCHEMBL17108591 | 0.80 | KMT2A (0.44) | KMT2AFABP5EPHX2FABP7CA1 | |
| SCHEMBL20511496 | 0.80 | KMT2A (0.51) | KMT2AFABP5EPHX2FABP7CA1 | |
| SCHEMBL30426077 | 0.80 | KMT2A (0.51) | KMT2AFABP5EPHX2FABP7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840736-B1 | IMPROVED SYNTHONS FOR THE SYNTHESIS AND DEPROTECTION OF PEPTIDE NUCLEIC ACIDS UNDER MILD CONDITIONS | PERSEPTIVE BIOSYSTEMS INC (US) | 2009-10-07 | — | — | EP | disclosed |
| EP-1873156-A1 | Process for the preparation of 6-[[(alkoxy)carbonyl]amino]-9H-Purine-9-acetic acid and 4-[(alkoxycarbonyl)amino]-2-oxo-1(2H)-Pyrimidineacetic acid derivatives as synthons for the synthesis of peptide nucleic acids | PerSeptive Biosystems, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| US-6172226-B1 | Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions | PERSEPTIVE BIOSYSTEMS, INC. | 2001-01-09 | — | — | US | disclosed |
| US-6133444-A | PURINE PEPTIDE NUCLEIC ACIDS SYNTHONS | PERSEPTIVE BIOSYSTEMS, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| EP-0840736-A1 | IMPROVED SYNTHONS FOR THE SYNTHESIS AND DEPROTECTION OF PEPTIDE NUCLEIC ACIDS UNDER MILD CONDITIONS | PerSeptive Biosystems, Inc. (US) | 1998-05-13 | — | — | EP | disclosed |
| WO-1996040685-A1 | IMPROVED SYNTHONS FOR THE SYNTHESIS AND DEPROTECTION OF PEPTIDE NUCLEIC ACIDS UNDER MILD CONDITIONS | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |