Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.42 |
| ▸ | PPARG | P37231 | 15/20 | 0.42 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 4/20 | 0.36 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384708 | 1.00 | PPARA (0.42) | PPARAPPARGPPARDSLC16A3SLC16A1 | |
| SCHEMBL4482467 | 1.00 | PPARA (0.42) | PPARAPPARGPPARDSLC16A3SLC16A1 | |
| SCHEMBL4382001 | 1.00 | PPARA (0.42) | PPARAPPARGPPARDSLC16A3SLC16A1 | |
| SCHEMBL5181005 | 0.96 | PPARA (0.40) | PPARAPPARGPPARDSLC16A3SLC16A1 | |
| SCHEMBL4377292 | 0.96 | PPARA (0.40) | PPARAPPARGPPARDSLC16A3SLC16A1 | |
| SCHEMBL1929331 | 0.92 | PPARA (0.43) | PPARAPPARGPPARDSLC16A3SLC16A1 | |
| SCHEMBL1929335 | 0.92 | PPARA (0.43) | PPARAPPARGPPARDSLC16A3SLC16A1 | |
| SCHEMBL4924261 | 0.92 | PPARA (0.45) | PPARAPPARGPPARD | |
| SCHEMBL4389972 | 0.91 | PPARG (0.40) | PPARAPPARGPPARDSLC16A3SLC16A1 | |
| SCHEMBL4388960 | 0.91 | PPARG (0.40) | PPARAPPARGPPARDSLC16A3SLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789402-B1 | 2-{-3-2-(PHENYL)-OXAZOL-4-YLMETHOXYMETHYL!-CYCLOHEXYLMETHOXY };-PROPIONIC ACID DERIVATIVES USED AS PPAR LIGANDES (PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS) FOR THE TREATMENT OF HYPERLIPIDAEMIE AND DIABETES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-18 | — | — | EP | claimed |
| US-7538131-B2 | 2-{-3-′2-(phenyl)-oxazol-4-ylmethoxymethyl-cyclohexylmethoxy}-propionic acid derivatives useful as peroxisome proliferator-activated receptor (PPAR) ligands for the treatment of hyperlipidemia and diabetes | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-05-26 | — | — | US | claimed |