Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.44 |
| ▸ | PPARG | P37231 | 17/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388972 | 1.00 | PPARA (0.44) | PPARAPPARGPPARD | |
| SCHEMBL4382008 | 1.00 | PPARA (0.44) | PPARAPPARGPPARD | |
| SCHEMBL5181646 | 0.92 | PPARA (0.38) | PPARAPPARGPPARD | |
| SCHEMBL4931721 | 0.91 | PPARA (0.38) | PPARAPPARGPPARD | |
| SCHEMBL4931702 | 0.91 | PPARA (0.38) | PPARAPPARGPPARD | |
| SCHEMBL4931706 | 0.91 | PPARA (0.38) | PPARAPPARGPPARD | |
| SCHEMBL4386752 | 0.91 | PPARA (0.46) | PPARAPPARGPPARD | |
| SCHEMBL4375409 | 0.91 | PPARA (0.46) | PPARAPPARGPPARD | |
| SCHEMBL4375407 | 0.91 | PPARA (0.46) | PPARAPPARGPPARD | |
| SCHEMBL3980560 | 0.91 | PPARA (0.43) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789402-B1 | 2-{-3-2-(PHENYL)-OXAZOL-4-YLMETHOXYMETHYL!-CYCLOHEXYLMETHOXY };-PROPIONIC ACID DERIVATIVES USED AS PPAR LIGANDES (PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS) FOR THE TREATMENT OF HYPERLIPIDAEMIE AND DIABETES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-18 | — | — | EP | claimed |