Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mannitol SCHEMBL27672183 | 0.83 | USP2 (0.40) | KDM4EKMT2AGFERRXFP1MEN1 | |
| SCHEMBL28558136 | 0.83 | IDO1 (0.42) | KDM4EKMT2AGFERRXFP1MEN1 | |
| SCHEMBL6013071 | 0.82 | NQO2 (0.39) | KDM4EKMT2AGFERRXFP1MEN1 | |
| SCHEMBL27691158 | 0.79 | KDM4E (0.35) | KDM4EKMT2AGFERRXFP1MEN1 | |
| SCHEMBL5028771 | 0.77 | KDM4E (0.48) | KDM4EKMT2AGFERRXFP1MEN1 | |
| SCHEMBL10609528 | 0.76 | KDM4E (0.54) | KDM4EKMT2AGFERRXFP1MEN1 | |
| SCHEMBL3371190 | 0.76 | TPMT (0.52) | KDM4EKMT2AGFERRXFP1MEN1 | |
| SCHEMBL31086817 | 0.76 | TPMT (0.41) | KDM4EKMT2AGFERRXFP1MEN1 | |
| SCHEMBL2888317 | 0.75 | KDM4E (0.54) | KDM4EKMT2AGFERRXFP1MEN1 | |
| SCHEMBL987442 | 0.75 | IDO1 (0.62) | KDM4EKMT2AGFERRXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105194693-A | Golden-shell covered iodo-nanoparticle for CT imaging and photo-thermal treatment and preparation of golden-shell covered iodo-nanoparticle | UNIV TIANJIN MEDICAL | 2015-12-30 | — | — | CN | claimed |
| US-4622367-A | X-ray contrast spherical hydrogel particles based on polymer and copolymers of acrylates and methacrylates and the method for preparation thereof | CESKOSLOVENSKA AKADEMIE VED (CS) | 1986-11-11 | — | — | US | claimed |
| JP-4208232-A | — | — | None | — | — | JP | disclosed |
| US-20230285601-A1 | NON DEGRADABLE RADIO-OPAQUE EMBOLISATION MICROSPHERE | GUERBET (FR) | 2023-09-14 | — | — | US | disclosed |
| EP-4041319-A1 | NON DEGRADABLE RADIO-OPAQUE EMBOLISATION MICROSPHERE | Guerbet (FR) | 2022-08-17 | — | — | EP | disclosed |
| CN-114555659-A | Nondegradable radiopaque embolic microspheres | 法国加栢 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021069528-A1 | NON DEGRADABLE RADIO-OPAQUE EMBOLISATION MICROSPHERE | GUERBET (FR) | 2021-04-15 | — | — | WO | disclosed |
| CN-101631577-A | Homogeneous, essentially radiopaque embolic particles | UNIV MAASTRICHT | 2010-01-20 | — | — | CN | disclosed |
| US-20090297612-A1 | HOMOGENEOUS, INTRINSIC RADIOPAQUE EMBOLIC PARTICLES | UNIVERSITEIT MAASTRICHT (NL) | 2009-12-03 | — | — | US | disclosed |
| EP-2125068-A2 | HOMOGENEOUS, INTRINSIC RADIOPAQUE EMBOLIC PARTICLES | Universiteit Maastricht (NL) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008054205-A2 | HOMOGENEOUS, INTRINSIC RADIOPAQUE EMBOLIC PARTICLES | UNIVERSITEIT MAASTRICHT (NL) | 2008-05-08 | — | — | WO | disclosed |
| JP-H04208232-A | X-RAY CONTRAST MATERIAL FOR GASTROINTESTIAL TRACT | SOVAK MILOS | 1992-07-29 | — | — | JP | disclosed |
| EP-0436316-A1 | X-ray contrast media for prolonged opacification | Sovak, Milos (US) | 1991-07-10 | — | — | EP | disclosed |
| US-4622367-A | X-ray contrast spherical hydrogel particles based on polymer and copolymers of acrylates and methacrylates and the method for preparation thereof | CESKOSLOVENSKA AKADEMIE VED (CS) | 1986-11-11 | — | — | US | disclosed |
| US-4622367-A | X-ray contrast spherical hydrogel particles based on polymer and copolymers of acrylates and methacrylates and the method for preparation thereof | CESKOSLOVENSKA AKADEMIE VED (CS) | 1986-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090297612-A1 | HOMOGENEOUS, INTRINSIC RADIOPAQUE EMBOLIC PARTICLES | MSR1, INO80C, H1-0 | KDM4E 3454/4885KMT2A 2075/4885GFER 4492/4885 |
| US-20230285601-A1 | NON DEGRADABLE RADIO-OPAQUE EMBOLISATION MICROSPHERE | KIT, TIE1, HRH4 | KDM4E 1031/4885KMT2A 1595/4885GFER 2731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.