SCHEMBL4382232

SCHEMBL4382232

CCCCC(CCCCCN=C=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
NR1I2 O75469 1/20 0.38
MMP2 P08253 3/20 0.35
MMP9 P14780 3/20 0.35
MMP12 P39900 1/20 0.35
NAAA Q02083 2/20 0.35
CYSLTR2 Q9NS75 1/20 0.35
CYSLTR1 Q9Y271 1/20 0.35
MMP1 P03956 1/20 0.34
MMP3 P08254 1/20 0.34
MMP14 P50281 1/20 0.34
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10888693 0.89 HDAC3 (0.38) NAAASIGMAR1
SCHEMBL17423122 0.81 NR1I2 (0.47) POLBNR1I2NAAACYSLTR2CYSLTR1
SCHEMBL3092233 0.81 NR1I2 (0.47) POLBNR1I2NAAACYSLTR2CYSLTR1
SCHEMBL10863122 0.81 NR1I2 (0.47) POLBNR1I2NAAACYSLTR2CYSLTR1
SCHEMBL6679763 0.81 NR1I2 (0.47) POLBNR1I2NAAACYSLTR2CYSLTR1
SCHEMBL6683946 0.81 NR1I2 (0.47) POLBNR1I2NAAACYSLTR2CYSLTR1
Hydrogen Sulfide SCHEMBL28214441 0.79 NR1I2 (0.46) POLBNR1I2NAAACYSLTR2CYSLTR1
SCHEMBL23849703 0.79 NR1I2 (0.49) NR1I2NAAACYSLTR2CYSLTR1SIGMAR1
SCHEMBL11369217 0.79 NR1I2 (0.49) NR1I2NAAACYSLTR2CYSLTR1SIGMAR1
SCHEMBL21633771 0.79 NR1I2 (0.49) NR1I2NAAACYSLTR2CYSLTR1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1423444-B9 AMPHOTERIC POLYMER RESINS THAT INCREASE THE RATE OF SIZING DEVELOPMENT HERCULES INC (US) 2009-11-18 EP disclosed
EP-1423444-B1 AMPHOTERIC POLYMER RESINS THAT INCREASE THE RATE OF SIZING DEVELOPMENT HERCULES INC (US) 2008-05-28 EP disclosed
CN-100343295-C Amphoteric polymer resins that increase the rate of sizing development HERCULES INC (US) 2007-10-17 CN disclosed
US-7270727-B2 Retention of brightness due to added optical brighteners HERCULES INCORPORATED (US) 2007-09-18 US disclosed
CN-1610708-A Amphoteric polymer resins that increase the rate of sizing development HERCULES INC (US) 2005-04-27 CN disclosed
EP-1423444-A1 AMPHOTERIC POLYMER RESINS THAT INCREASE THE RATE OF SIZING DEVELOPMENT HERCULES INCORPORATED (US) 2004-06-02 EP disclosed
US-20040016528-A1 Paper sized with a sizing agent and a selected sizing promoter BIRKO CORPORATION 2004-01-29 US disclosed
US-20030127204-A1 Amphoteric polymer resins that increase the rate of sizing development HERCULES CORPORATION 2003-07-10 US disclosed
WO-2003022898-A1 AMPHOTERIC POLYMER RESINS THAT INCREASE THE RATE OF SIZING DEVELOPMENT HERCULES INCORPORATED (US) 2003-03-20 WO disclosed
US-5853542-A Method of sizing paper using a sizing agent and a polymeric enhancer and paper produced thereof HERCULES INCORPORATED (US) 1998-12-29 US disclosed
US-4522686-A KETENE DIMER, ROSIN AND NITROGEN CONTAIN CATIONIC DISPERSANT HERCULES INCORPORATED (US) 1985-06-11 US disclosed
EP-0093321-A1 Sizing agent based on ketene dimers BAYER AG (DE) 1983-11-09 EP disclosed
US-4383077-A CATIONIC RESINS) POLYAMIDE-AMINO RESIN COPOLYMERS; WATER SOLUBILITY; PAPERMAKING; SIZING HERCULES INCORPORATED (US) 1983-05-10 US disclosed
US-4382129-A POLYAMINOPOLYAMIDE HERCULES INCORPORATED (US) 1983-05-03 US disclosed
US-4380602-A Water-soluble thermosettable resinous compositions containing dicyandiamide-formaldehyde condensates modified with epihalohydrin and process for preparing the same HERCULES INCORPORATED (US) 1983-04-19 US disclosed
US-4380603-A CATIONIC POLYMERS, SIZING HERCULES INCORPORATED (US) 1983-04-19 US disclosed
EP-0074544-A1 Aqueous sizing compositions HERCULES INCORPORATED (US) 1983-03-23 EP disclosed
US-4295931-A POLYDIALLYLAMINE-EPIHALOHYDRIN RESIN, KETENE DIMER OR ANHYDRIDE OR ISOCYANATE, PAPER HERCULES INCORPORATED (US) 1981-10-20 US disclosed
US-4279794-A FOR PAPER, USING A KETENE DIMER SIZING AGENT AND A POLY(DIALLYLAMINE) EPIHALOHYDRIN RESIN AS ACCELERATOR HERCULES INCORPORATED (US) 1981-07-21 US disclosed
US-4243481-A PAPER REACTIVE SIZE, ANHYDRIDES, KETENE DIMER, ISOCYANATES; CATIONIC POLYMER PROMOTERS HERCULES INCORPORATED (US) 1981-01-06 US disclosed