SCHEMBL4383659

SCHEMBL4383659

C=C(O)C(=O)OCCc1ccc(C)cc1-n1nc2ccccc2n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.49
RAB9A P51151 9/20 0.49
ALDH1A1 P00352 6/20 0.49
SMN1; SMN2 Q16637 6/20 0.49
KDM4E B2RXH2 6/20 0.47
MAPT P10636 6/20 0.47
HPGD P15428 5/20 0.47
TDP1 Q9NUW8 2/20 0.47
POLB P06746 2/20 0.47
LMNA P02545 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
IGF2BP2 Q9Y6M1 1/20 0.39
THRB P10828 1/20 0.39
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29315787 0.91 NPC1 (0.52) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29315785 0.84 NPC1 (0.50) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29315729 0.84 NPC1 (0.49) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29315784 0.84 NPC1 (0.49) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29315792 0.83 NPC1 (0.48) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29315782 0.83 NPC1 (0.48) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL4445959 0.78 NPC1 (0.48) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29315731 0.78 NPC1 (0.47) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL8676078 0.77 NPC1 (0.40) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29315733 0.77 NPC1 (0.46) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1113051-B1 Water-based ink KAO CORP (JP) 2009-11-18 EP disclosed
EP-1006161-B1 INK COMPOSITION PROVIDING IMAGE EXCELLENT IN LIGHT STABILITY SEIKO EPSON CORP (JP) 2007-05-30 EP disclosed
EP-1125760-B1 RECORDING METHOD COMPRISING PRINTING RECORDING MEDIUM WITH TWO LIQUID COMPONENTS SEIKO EPSON CORP (JP) 2006-05-17 EP disclosed
US-7040747-B2 Recording method for printing using two liquids on recording medium SEIKO EPSON CORPORATION (JP) 2006-05-09 US disclosed
US-6972303-B1 Ink composition providing image excellent in light stability SEIKO EPSON CORPORATION (JP) 2005-12-06 US disclosed
US-6933330-B2 Mixture of coloring agent and aqueous polymer dispersion KAO CORPORATION (JP) 2005-08-23 US disclosed
US-6590012-B2 Comprising a colorant, water, a water- soluble organic solvent, and a fine particle of a polymer which comprising a polymer having film-forming property and ultraviolet absorbing and/or light stabilizing capability SEIKO EPSON CORPORATION (JP) 2003-07-08 US disclosed
US-20030069329-A1 Recording method for printing using two liquids on recording medium SEIKO EPSON CORPORATION 2003-04-10 US disclosed
US-6439708-B1 INK JET RECORDING WITH WATERPROFING AND COLORFASTNESS SEIKO EPSON CORPORATION (JP) 2002-08-27 US disclosed
US-20010023265-A1 Water-based ink FUJITSU LIMITED (JP) 2001-09-20 US disclosed
EP-1125760-A1 RECORDING METHOD COMPRISING PRINTING RECORDING MEDIUM WITH TWO LIQUID COMPONENTS SEIKO EPSON CORPORATION (JP) 2001-08-22 EP disclosed
US-20010009933-A1 INK COMPOSITION CAPABLE OF REALIZING LIGHT FAST IMAGE SEIKO EPSON CORPORATION (JP) 2001-07-26 US disclosed
EP-1113051-A1 Water-based ink Kao Corporation (JP) 2001-07-04 EP disclosed
EP-1022151-A1 METHOD OF INK-JET RECORDING WITH TWO FLUIDS SEIKO EPSON CORPORATION (JP) 2000-07-26 EP disclosed
EP-1006161-A1 INK COMPOSITION PROVIDING IMAGE EXCELLENT IN LIGHT STABILITY SEIKO EPSON CORPORATION (JP) 2000-06-07 EP disclosed
EP-0875544-A1 Ink composition capable of realizing light fast image SEIKO EPSON CORPORATION (JP) 1998-11-04 EP disclosed