⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382426 | 0.75 | — | — | |
| SCHEMBL4388029 | 0.74 | — | — | |
| SCHEMBL4384797 | 0.74 | — | — | |
| SCHEMBL13253387 | 0.72 | MAPT (0.33) | — | |
| SCHEMBL4383543 | 0.71 | TSHR (0.34) | — | |
| SCHEMBL10029817 | 0.68 | ATM (0.31) | — | |
| SCHEMBL4383483 | 0.68 | MAPK1 (0.34) | — | |
| SCHEMBL4382421 | 0.68 | — | — | |
| SCHEMBL4386117 | 0.67 | POLB (0.38) | — | |
| SCHEMBL4382168 | 0.66 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629424-B2 | Metal-containing compositions and method of making same | PRYOG, LLC (US) | 2009-12-08 | — | — | US | claimed |
| US-20080015278-A1 | Metal-Containing Compositions and Method of Making Same | PRYOG, LLC | 2008-01-17 | — | — | US | claimed |
| US-7629424-B2 | Metal-containing compositions and method of making same | PRYOG, LLC (US) | 2009-12-08 | — | — | US | disclosed |
| US-20080015278-A1 | Metal-Containing Compositions and Method of Making Same | PRYOG, LLC | 2008-01-17 | — | — | US | disclosed |