Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4378095 | 0.89 | HRH3 (0.88) | HRH3POLB | |
| Hydrochloric Acid SCHEMBL4382136 | 0.88 | HRH3 (0.91) | HRH3POLB | |
| SCHEMBL4377725 | 0.86 | HRH3 (0.97) | HRH3POLB | |
| Hydrochloric Acid SCHEMBL4378983 | 0.85 | HRH3 (1.00) | HRH3POLB | |
| SCHEMBL4377304 | 0.85 | HRH3 (0.97) | HRH3POLBTACR1 | |
| Hydrochloric Acid SCHEMBL4382044 | 0.84 | HRH3 (1.00) | HRH3POLBTACR1 | |
| SCHEMBL4377512 | 0.75 | HRH3 (0.76) | HRH3POLB | |
| Hydrochloric Acid SCHEMBL4381928 | 0.74 | HRH3 (0.78) | HRH3POLB | |
| SCHEMBL4383722 | 0.73 | HRH3 (0.65) | HRH3POLB | |
| SCHEMBL4376061 | 0.72 | HRH3 (0.88) | HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421071-B1 | SUBSTITUTED PIPERAZINE AND DIAZEPANE DERIVAIVES AS HISTAMINE H3 RECEPTOR MODULATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2009-11-18 | — | — | EP | claimed |