Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22656590 | 0.72 | GABRR1 (0.50) | TSHRLMNAKMT2A | |
| SCHEMBL27224128 | 0.72 | GABRR1 (0.50) | TSHRLMNAKMT2A | |
| SCHEMBL109579 | 0.72 | GABRR1 (0.50) | TSHRLMNAKMT2A | |
| SCHEMBL4382168 | 0.71 | TSHR (0.34) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL28992700 | 0.70 | GABRR1 (0.48) | TSHRLMNAKMT2A | |
| SCHEMBL4386564 | 0.69 | SLC1A2 (0.32) | LMNAKMT2A | |
| SCHEMBL4384475 | 0.67 | GABRR1 (0.30) | — | |
| SCHEMBL28696968 | 0.62 | GABRR1 (0.50) | TSHRLMNAKMT2A | |
| SCHEMBL21905245 | 0.62 | GABRR1 (0.50) | TSHRLMNAKMT2A | |
| SCHEMBL17008604 | 0.62 | GABRR1 (0.50) | TSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015278-A1 | Metal-Containing Compositions and Method of Making Same | PRYOG, LLC | 2008-01-17 | — | — | US | claimed |
| WO-2007070092-A2 | METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME | PRYOG, LLC (US) | 2007-06-21 | — | — | WO | claimed |
| US-7629424-B2 | Metal-containing compositions and method of making same | PRYOG, LLC (US) | 2009-12-08 | — | — | US | disclosed |
| US-20080015278-A1 | Metal-Containing Compositions and Method of Making Same | PRYOG, LLC | 2008-01-17 | — | — | US | disclosed |
| WO-2007070092-A2 | METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME | PRYOG, LLC (US) | 2007-06-21 | — | — | WO | disclosed |