Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.38 |
| ▸ | PPARA | Q07869 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 5/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 5/20 | 0.36 |
| ▸ | MCTS1 | Q9ULC4 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484164 | 0.96 | PPARG (0.40) | PPARGPPARAALDH1A1MEN1KMT2A | |
| SCHEMBL4478661 | 0.96 | PPARG (0.40) | PPARGPPARAALDH1A1MEN1KMT2A | |
| SCHEMBL4382433 | 0.96 | PPARG (0.40) | PPARGPPARAALDH1A1MEN1KMT2A | |
| SCHEMBL4482451 | 0.96 | PPARG (0.40) | PPARGPPARAALDH1A1MEN1KMT2A | |
| SCHEMBL4373520 | 0.96 | PPARG (0.40) | PPARGPPARAALDH1A1MEN1KMT2A | |
| SCHEMBL4377242 | 0.91 | PPARA (0.39) | PPARGPPARAPPARDCETP | |
| SCHEMBL4382436 | 0.90 | PPARA (0.39) | PPARGPPARAALDH1A1MEN1KMT2A | |
| SCHEMBL4389989 | 0.89 | SLC16A3 (0.42) | ALDH1A1KMT2ASLC16A3SLC16A1MCTS1 | |
| SCHEMBL4383910 | 0.89 | SLC16A3 (0.42) | ALDH1A1KMT2ASLC16A3SLC16A1MCTS1 | |
| SCHEMBL4391944 | 0.88 | PPARG (0.38) | PPARGPPARASLC16A3SLC16A1MCTS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789402-B1 | 2-{-3-2-(PHENYL)-OXAZOL-4-YLMETHOXYMETHYL!-CYCLOHEXYLMETHOXY };-PROPIONIC ACID DERIVATIVES USED AS PPAR LIGANDES (PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS) FOR THE TREATMENT OF HYPERLIPIDAEMIE AND DIABETES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-18 | — | — | EP | disclosed |