Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 19/20 | 0.66 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3738823 | 0.96 | PTPN1 (0.72) | PTPN1 | |
| Trifluoroacetic Acid SCHEMBL3739138 | 0.95 | PTPN1 (0.72) | PTPN1 | |
| SCHEMBL13040945 | 0.90 | PTPN1 (0.80) | PTPN1 | |
| SCHEMBL4389723 | 0.90 | PTPN1 (0.80) | PTPN1 | |
| Trifluoroacetic Acid SCHEMBL3727506 | 0.85 | PTPN1 (0.73) | PTPN1 | |
| Trifluoroacetic Acid SCHEMBL3729135 | 0.85 | PTPN1 (0.76) | PTPN1 | |
| Trifluoroacetic Acid SCHEMBL3742933 | 0.84 | PTPN1 (0.75) | PTPN1 | |
| Trifluoroacetic Acid SCHEMBL3728964 | 0.83 | PTPN1 (0.72) | PTPN1 | |
| Trifluoroacetic Acid SCHEMBL3737675 | 0.83 | PTPN1 (0.72) | PTPN1 | |
| Trifluoroacetic Acid SCHEMBL3734678 | 0.83 | PTPN1 (0.88) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910359-B1 | PYRIDO [2 , 3-D]PYRIMIDINE-2 , 4-DIAMINE COMPOUNDS AS PTPlB INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-18 | — | — | EP | disclosed |