Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4376642 | 0.99 | MAPK14 (0.51) | MAPK14 | |
| SCHEMBL13610744 | 0.88 | MAPK14 (0.50) | MAPK14 | |
| SCHEMBL13602931 | 0.87 | MAPK14 (0.52) | MAPK14 | |
| SCHEMBL13610862 | 0.86 | MAPK14 (0.55) | MAPK14 | |
| Hydrochloric Acid SCHEMBL4379526 | 0.86 | MAPK14 (0.51) | MAPK14 | |
| SCHEMBL4379497 | 0.85 | MAPK14 (0.50) | MAPK14 | |
| SCHEMBL4386829 | 0.85 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL4381554 | 0.84 | MAPK14 (0.51) | MAPK14 | |
| SCHEMBL4385221 | 0.83 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL5270020 | 0.82 | MAPK14 (0.53) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| EP-1490064-B1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORP (US) | 2009-11-18 | — | — | EP | disclosed |