Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.52 |
| ▸ | MINK1 | Q8N4C8 | 3/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 14/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | MARK3 | P27448 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3743573 | 0.88 | MAP4K4 (0.58) | MAP4K4MINK1PRKCDS1PR1S1PR3 | |
| SCHEMBL3745599 | 0.84 | MAP4K4 (0.56) | MAP4K4MINK1PRKCDS1PR1S1PR3 | |
| SCHEMBL3740077 | 0.84 | MAP4K4 (0.53) | MAP4K4MINK1PRKCDS1PR1S1PR3 | |
| SCHEMBL3740654 | 0.83 | MAP4K4 (0.55) | MAP4K4MINK1PRKCDS1PR1S1PR3 | |
| SCHEMBL13045319 | 0.83 | MAP4K4 (0.53) | MAP4K4MINK1PRKCDS1PR1S1PR3 | |
| SCHEMBL3749362 | 0.82 | MAP4K4 (0.54) | MAP4K4MINK1PRKCDS1PR1S1PR3 | |
| SCHEMBL3747416 | 0.82 | MAPK1 (0.58) | MAP4K4MINK1PRKCDS1PR1S1PR3 | |
| SCHEMBL3736447 | 0.81 | MAP4K4 (0.53) | MAP4K4MINK1PRKCDS1PR1S1PR3 | |
| SCHEMBL3741627 | 0.81 | MAP4K4 (0.53) | MAP4K4MINK1PRKCDS1PR1S1PR3 | |
| SCHEMBL3747540 | 0.81 | S1PR1 (0.53) | MAP4K4MINK1PRKCDS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2109364-A1 | NOVEL OXADIAZOLE COMPOUNDS | Abbott Laboratories (US) | 2009-10-21 | — | — | EP | disclosed |
| WO-2008076356-A1 | NOVEL OXADIAZOLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2008-06-26 | — | — | WO | disclosed |