SCHEMBL43851

SCHEMBL43851

Nc1ccc(CC(N)C(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.71
PTGS1 P23219 3/20 0.70
ALPI P09923 1/20 0.70
PKM P14618 1/20 0.70
XIAP P98170 1/20 0.70
HIF1A Q16665 5/20 0.59
ALOX15 P16050 3/20 0.59
KDM4E B2RXH2 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
HSD17B10 Q99714 2/20 0.59
USP2 O75604 1/20 0.59
EGFR P00533 1/20 0.59
LCK P06239 1/20 0.59
FYN P06241 1/20 0.59
ADORA3 P0DMS8 1/20 0.59
HTR2A P28223 1/20 0.59
PTGS2 P35354 1/20 0.59
RECQL P46063 1/20 0.59
TPH1 P17752 1/20 0.59
GRB2 P62993 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288375 1.00 SLC7A5 (0.71) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL43852 1.00 SLC7A5 (0.71) SLC7A5PTGS1ALPIPKMXIAP
Water SCHEMBL2776212 0.98 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL28269648 0.98 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Water SCHEMBL2778595 0.98 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL3873365 0.98 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Water SCHEMBL2310847 0.98 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL27245458 0.96 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL31369911 0.94 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL16207858 0.94 SLC7A5 (0.81) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10088 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 CN claimed
US-12577575-B2 Methods and compositions for promoting non-natural amino acid-containing protein production AMBRX, INC. (US) 2026-03-17 US claimed
EP-3448417-B1 INSULIN DIMER-INCRETIN CONJUGATES MERCK SHARP & DOHME LLC (US) 2025-11-12 EP claimed
EP-4626479-A1 COMPOSITIONS AND METHODS FOR PROTEIN INTERNALIZATION Lytica Therapeutics, Inc. (US) 2025-10-08 EP claimed
US-12428447-B2 Peptide-based non-proteinaceous cargo delivery FELDAN BIO INC. (CA) 2025-09-30 US claimed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP claimed
US-12404512-B2 Method for optimizing antibody expression AMBRX, INC. (US) 2025-09-02 US claimed
US-20250270289-A1 SEQUENCE-DEFINED POLYMERS WITH ONE OR MORE AZIDES, METHODS OF MAKING, AND METHODS OF USE THEREOF YALE UNIVERSITY 2025-08-28 US claimed
EP-3788149-B1 A METHOD FOR OPTIMIZING ANTIBODY EXPRESSION AMBRX INC (US) 2025-08-27 EP claimed
US-12377294-B2 Anti-CD3 antibody folate bioconjugates and their uses AMBRX, INC. (US) 2025-08-05 US claimed
US-4601981-A Enzymatically active protein-enzyme complex membranes RESEARCH CORPORATION (US) 1986-07-22 US claimed
EP-0183006-A2 A recombinant DNA-molecule, coryneform bacteria carrying recombinant DNA and process for producing an aromatic amino acid by using the same AJINOMOTO CO., INC. (JP) 1986-06-04 EP claimed
EP-0076557-B1 PEPTIDES AND PSEUDOPEPTIDES IN WHICH THE N TERMINUS BEARS TWO SUBSTITUENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-11-13 EP claimed
US-4421744-A OPIATE RECEPTOR ANTAGONISTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-12-20 US claimed
US-4407952-A OF GENETICALLY ENGINEERED ESCHERICHIA AJINOMOTO COMPANY INCORPORATED (JP) 1983-10-04 US claimed
EP-0076557-A2 Peptides and pseudopeptides in which the N terminus bears two substituents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-13 EP claimed
US-4305926-A Immobilization of Streptokinase EVERSE, KATHLEEN E. 1981-12-15 US claimed
US-4116949-A WATER-SOLUBLE, PHYSIOLOGICALLY ACTIVE, SYNTHETIC COPOLYPEPTIDES THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1978-09-26 US claimed
US-3972776-A Preparation of protein membranes containing microbial cells RESEARCH CORPORATION (US) 1976-08-03 US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed