Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 15/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4386122 | 0.92 | TSHR (0.61) | TSHRTHRB | |
| SCHEMBL7372256 | 0.85 | TSHR (0.59) | TSHRTHRBPOLB | |
| Hydrochloric Acid SCHEMBL4109529 | 0.84 | TSHR (0.58) | TSHRTHRBPOLB | |
| SCHEMBL1341702 | 0.81 | TSHR (0.43) | TSHRLMNAPOLB | |
| Hydrochloric Acid SCHEMBL4123503 | 0.80 | TSHR (0.42) | TSHRLMNAPOLB | |
| SCHEMBL18138091 | 0.80 | TSHR (0.42) | TSHRLMNAPOLB | |
| Hydrochloric Acid SCHEMBL16528079 | 0.80 | TSHR (0.42) | TSHRLMNAPOLB | |
| SCHEMBL16265723 | 0.78 | TSHR (0.41) | TSHRLMNAPOLBKAT2B | |
| Ethyl Propionate SCHEMBL11668791 | 0.77 | TSHR (0.40) | TSHRLMNAPOLB | |
| SCHEMBL26097101 | 0.77 | TSHR (0.54) | TSHRLMNAPOLBKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306059-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-10 | — | — | US | disclosed |
| EP-1889835-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | Daiichi Sankyo Company, Limited (JP) | 2008-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306059-A1 | CYCLIC AMINE DERIVATIVE HAVING SUBSTITUTED ALKYL GROUP | CBR3, CNR1, C3AR1 | TSHR 131/4885THRB 1647/4885LMNA 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.