SCHEMBL4386473

SCHEMBL4386473

CCN(CC)c1ccc(C(=CC=C(c2ccccc2)c2ccccc2)c2ccc(N(Cc3ccccc3)Cc3ccccc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.57
CNR2 P34972 8/20 0.57
CYP2C19 P33261 1/20 0.51
NR1H2 P55055 2/20 0.49
NR1H3 Q13133 2/20 0.49
TDP1 Q9NUW8 2/20 0.48
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MITF O75030 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
MAPK1 P28482 1/20 0.48
RAD52 P43351 1/20 0.48
KMT2A Q03164 1/20 0.48
ESRRG P62508 2/20 0.46
PPARG P37231 1/20 0.46
HDAC6 Q9UBN7 1/20 0.45
MGLL Q99685 1/20 0.43
CNR1 P21554 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7861988 1.00 TSHR (0.57) TSHRCNR2CYP2C19NR1H2NR1H3
SCHEMBL10106026 0.92 CYP2C19 (0.55) TSHRCNR2CYP2C19NR1H2NR1H3
SCHEMBL14256373 0.92 TSHR (0.53) TSHRCNR2CYP2C19NR1H2NR1H3
SCHEMBL10111286 0.92 CYP2C19 (0.58) TSHRCNR2CYP2C19ESRRGPPARG
SCHEMBL141631 0.91 TDP1 (0.51) TSHRCNR2TDP1ALDH1A1KDM4E
SCHEMBL7884419 0.91 TDP1 (0.51) TSHRCNR2TDP1ALDH1A1KDM4E
SCHEMBL9408477 0.91 TDP1 (0.51) TSHRCNR2TDP1ALDH1A1KDM4E
SCHEMBL8579335 0.91 TDP1 (0.51) TSHRCNR2TDP1ALDH1A1KDM4E
SCHEMBL8579332 0.91 TDP1 (0.51) TSHRCNR2TDP1ALDH1A1KDM4E
SCHEMBL7884421 0.91 TDP1 (0.51) TSHRCNR2TDP1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629096-B2 Electrophotographic photoreceptor with an undercoat layer containing a polyimide resin and electrophotographic apparatus with the photoreceptor YAMANASHI ELECTRONICS CO., LTD. (JP) 2009-12-08 US claimed
US-20070148574-A1 Electrophotographic photoreceptor and electrophotographic apparatus YAMANASHI ELECTRONICS CO., LTD. (JP) 2007-06-28 US claimed
US-5837411-A MULTILAYER ELEMENTS AS PHOTORECEPTORS WITH CHARGE GENERATING LAYERS HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-11-17 US claimed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-8097393-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2012-01-17 US disclosed
US-8097393-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2012-01-17 US disclosed
US-7629096-B2 Electrophotographic photoreceptor with an undercoat layer containing a polyimide resin and electrophotographic apparatus with the photoreceptor YAMANASHI ELECTRONICS CO., LTD. (JP) 2009-12-08 US disclosed
US-7629096-B2 Electrophotographic photoreceptor with an undercoat layer containing a polyimide resin and electrophotographic apparatus with the photoreceptor YAMANASHI ELECTRONICS CO., LTD. (JP) 2009-12-08 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20070231733-A1 IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2007-10-04 US disclosed
US-20070231733-A1 IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2007-10-04 US disclosed
US-20070148574-A1 Electrophotographic photoreceptor and electrophotographic apparatus YAMANASHI ELECTRONICS CO., LTD. (JP) 2007-06-28 US disclosed
US-20070148574-A1 Electrophotographic photoreceptor and electrophotographic apparatus YAMANASHI ELECTRONICS CO., LTD. (JP) 2007-06-28 US disclosed
EP-0810267-B1 Oxytitanium phthalocyanine crystal NEC CORP (JP) 2001-11-21 EP disclosed
US-5876892-A POLYCARBONATESILOXANE COPOLYMER SHINDENGEN ELECTRIC MANUFACTURING CO., LTD (JP) 1999-03-02 US disclosed
US-5831084-A FINENESS PARTICLE SIZE; STABILITY; PHOTOSENSITIVITY TO LONG WAVELENGTHS NEC CORPORATION (JP) 1998-11-03 US disclosed
EP-0810267-A2 Oxytitanium phthalocyanine crystal NEC CORPORATION (JP) 1997-12-03 EP disclosed
US-5443933-A Laminate consists of a electroconductive support, hydroxy titanium pthalocyanine as charge generating layer and butadiene compound as charge-transfer layer deposited on the support, a monophenolic antioxidant and dielectric binder SHINDENGEN ELECTRIC MANUFACTURING CO., LTD. (JP) 1995-08-22 US disclosed