Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4386507 | 0.73 | GSK3B (0.35) | ADORA2BGSK3BCAMKK2 | |
| SCHEMBL8234644 | 0.60 | GSK3B (0.47) | GSK3B | |
| SCHEMBL1830258 | 0.59 | GSK3B (0.49) | GSK3B | |
| SCHEMBL1833018 | 0.58 | GSK3B (0.48) | GSK3B | |
| SCHEMBL1832336 | 0.57 | GSK3B (0.47) | GSK3B | |
| SCHEMBL2065123 | 0.57 | GSK3B (0.47) | GSK3B | |
| SCHEMBL18060303 | 0.57 | KDM4E (0.48) | — | |
| SCHEMBL18060187 | 0.57 | KDM4E (0.48) | — | |
| SCHEMBL13910999 | 0.56 | HSP90AA1 (0.50) | GSK3BCDC7 | |
| SCHEMBL2064851 | 0.56 | GSK3B (0.48) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121635-A2 | SUBSTITUTED HETEROARYL PYRIDOPYRIMIDONE DERIVATIVES | Sanofi-Aventis (FR) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008078196-A2 | SUBSTITUTED HETEROARYL PYRIDOPYRIMIDONE DERIVATIVES | SANOFI-AVENTIS (FR) | 2008-07-03 | — | — | WO | disclosed |