Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 7/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891727 | 0.79 | GRIK1 (0.64) | GRIK1GRIK2CPA1CYP2C19CHRM1 | |
| SCHEMBL6050002 | 0.77 | GRIK1 (0.75) | GRIK1GRIK2CPA1CYP2C19CHRM1 | |
| SCHEMBL629461 | 0.76 | — | — | |
| SCHEMBL9138443 | 0.75 | GRIK1 (0.50) | GRIK1GRIK2CPA1CYP2C19CHRM1 | |
| Hydrogen Sulfide SCHEMBL27837245 | 0.74 | GRIK1 (0.53) | GRIK1GRIK2CPA1CYP2C19CHRM1 | |
| SCHEMBL10625605 | 0.73 | — | — | |
| 4-En-Metabolite SCHEMBL1000796 | 0.72 | CHRM1 (0.62) | GRIK1GRIK2CPA1CYP2C19CHRM1 | |
| SCHEMBL1885655 | 0.72 | GRIK1 (0.62) | GRIK1GRIK2CPA1CYP2C19 | |
| 4-En-Metabolite SCHEMBL9111371 | 0.72 | CHRM1 (0.62) | GRIK1GRIK2CPA1CYP2C19CHRM1 | |
| SCHEMBL4795102 | 0.72 | GRIK1 (0.62) | GRIK1GRIK2CPA1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629400-B2 | Image making medium | HYMAN SYDNEY | 2009-12-08 | — | — | US | disclosed |
| US-20030035917-A1 | Image making medium | HYMAN SYDNEY (US) | 2003-02-20 | — | — | US | disclosed |
| US-6518305-B1 | For inhibiting neuraminidases from disease- causing microorganisms, especially, influenza neuraminidase | ABBOTT LABORATORIES | 2003-02-11 | — | — | US | disclosed |
| WO-2001028979-A2 | INHIBITORS OF NEURAMINIDASES | ABBOTT LABORATORIES (US) | 2001-04-26 | — | — | WO | disclosed |
| EP-1087938-A1 | INHIBITORS OF NEURAMINIDASES | ABBOTT LABORATORIES (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999054290-A1 | INHIBITORS OF NEURAMINIDASES | ABBOTT LABORATORIES (US) | 1999-10-28 | — | — | WO | disclosed |