Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2688628 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1CYP1A2 | |
| SCHEMBL334921 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1CYP1A2 | |
| SCHEMBL3351227 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1CYP1A2 | |
| SCHEMBL6126545 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1CYP1A2 | |
| SCHEMBL14151679 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1CYP1A2 | |
| SCHEMBL14151678 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1CYP1A2 | |
| SCHEMBL4420799 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1CYP1A2 | |
| SCHEMBL4941984 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1CYP1A2 | |
| SCHEMBL182454 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1CYP1A2 | |
| SCHEMBL4941987 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129224-A1 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | Anadys Pharmaceuticals, Inc. (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008124450-A1 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | ANADYS PHARMACEUTICALS, INC. (US) | 2008-10-16 | — | — | WO | disclosed |