Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | ESRRB | O95718 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1724358 | 0.86 | TYR (0.48) | TYRHSD17B3ALOX15MEN1TP53 | |
| SCHEMBL30979257 | 0.86 | TYR (0.48) | TYRHSD17B3ALOX15MEN1TP53 | |
| SCHEMBL4391901 | 0.83 | TYR (0.48) | TYRHSD17B3ALOX15MEN1TP53 | |
| SCHEMBL1046128 | 0.83 | BACE1 (0.50) | TYRALOX15BACE1MEN1TP53 | |
| SCHEMBL9579057 | 0.82 | TYR (0.56) | TYRHSD17B3ALOX15MEN1TP53 | |
| SCHEMBL2571546 | 0.82 | TYR (0.45) | TYRHSD17B3ALOX15MEN1TP53 | |
| SCHEMBL5381354 | 0.80 | TYR (0.48) | TYRHSD17B3ALOX15MEN1TP53 | |
| Phosphoric Acid SCHEMBL4636546 | 0.78 | TYR (0.42) | TYRHSD17B3ALOX15MEN1TP53 | |
| SCHEMBL27795646 | 0.78 | TYR (0.52) | TYRHSD17B3ALOX15MEN1TP53 | |
| SCHEMBL1425128 | 0.77 | CA12 (0.48) | TYRHSD17B3ALOX15BACE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227390-B2 | Binder resin for friction material, binder resin composition for friction material, composite material for friction material containing the same, friction material and production method thereof | AKEBONO BRAKE INDUSTRY CO., LTD. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-20090137434-A1 | BINDER RESIN FOR FRICTION MATERIAL, BINDER RESIN COMPOSITION FOR FRICTION MATERIAL, COMPOSITE MATERIAL FOR FRICTION MATERIAL CONTAINING THE SAME, FRICTION MATERIAL AND PRODUCTION METHOD THEREOF | AKEBONO BRAKE INDUSTRY CO., LTD (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-0036555-A1 | Zinc chloride complex derivatives, preparation and use thereof, and process for the preparation of phenoxazine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-30 | — | — | EP | disclosed |