⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387908 | 1.00 | — | — | |
| SCHEMBL1524402 | 0.78 | HPGD (0.31) | — | |
| SCHEMBL1524477 | 0.78 | HPGD (0.31) | — | |
| SCHEMBL1524401 | 0.78 | HPGD (0.31) | — | |
| SCHEMBL8520266 | 0.71 | — | — | |
| SCHEMBL6881512 | 0.71 | — | — | |
| SCHEMBL6881519 | 0.71 | — | — | |
| SCHEMBL15796466 | 0.69 | — | — | |
| SCHEMBL336094 | 0.69 | — | — | |
| SCHEMBL9311468 | 0.69 | HPGD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629400-B2 | Image making medium | HYMAN SYDNEY | 2009-12-08 | — | — | US | disclosed |
| US-6593480-B2 | Obesity, hyperglycemia | ABBOTT LABORATORIES | 2003-07-15 | — | — | US | disclosed |
| US-20030035917-A1 | Image making medium | HYMAN SYDNEY (US) | 2003-02-20 | — | — | US | disclosed |
| WO-2002070507-A2 | GLYCORTICOID RECEPTOR ANTAGONISTS FOR TREATMENT OF DIABETES | ABBOTT LABORATORIES (US) | 2002-09-12 | — | — | WO | disclosed |
| US-20010041802-A1 | Glucocorticoid receptor antagonists for treatment of diabetes | KARO BIO AB (SE) | 2001-11-15 | — | — | US | disclosed |
| EP-0049026-B1 | POLYSILOXANE EMULSION ELASTOMERS REINFORCED WITH EMULSIFIED ORGANO-SILICONE COPOLYMERS | DOW CORNING CORPORATION (US) | 1985-01-30 | — | — | EP | disclosed |
| WO-1982001190-A1 | POLYSILOXANE EMULSION ELASTOMERS REINFORCED WITH EMULSIFIED ORGANO-SILICONE COPOLYMERS | DOW CORNING (US) | 1982-04-15 | — | — | WO | disclosed |
| EP-0049026-A1 | Polysiloxane emulsion elastomers reinforced with emulsified organo-silicone copolymers | DOW CORNING CORPORATION (US) | 1982-04-07 | — | — | EP | disclosed |
| US-4288356-A | VINYLSILANE ADDITION COPOLYMER | DOW CORNING CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |