SCHEMBL4388210

SCHEMBL4388210

CC(=O)NC1c2ccccc2Oc2ccccc21

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.56
MEN1 O00255 3/20 0.54
HDAC3 O15379 1/20 0.51
HDAC4 P56524 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC10 Q969S8 1/20 0.51
HDAC11 Q96DB2 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
HDAC9 Q9UKV0 1/20 0.51
HDAC5 Q9UQL6 1/20 0.51
ATM Q13315 1/20 0.50
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
USP2 O75604 1/20 0.47
HSD17B2 P37059 1/20 0.47
FFAR4 Q5NUL3 1/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11797713 0.88 KMT2A (0.47) KMT2AMEN1HDAC3HDAC4HDAC1
SCHEMBL2893619 0.85 KMT2A (0.55) KMT2AMEN1HDAC3HDAC4HDAC1
SCHEMBL27819399 0.82 KMT2A (0.78) KMT2AMEN1HDAC3HDAC4HDAC1
SCHEMBL2893865 0.81 ATM (0.59) KMT2AMEN1HDAC3HDAC4HDAC1
SCHEMBL29365092 0.81 ATM (0.59) KMT2AMEN1HDAC3HDAC4HDAC1
SCHEMBL3945217 0.81 KMT2A (0.52) KMT2AMEN1HDAC3HDAC4HDAC1
SCHEMBL9172897 0.81 KMT2A (0.52) KMT2AMEN1HDAC3HDAC4HDAC1
SCHEMBL11871629 0.79 ATM (0.51) KMT2AMEN1HDAC3HDAC4HDAC1
SCHEMBL144326 0.79 KMT2A (0.65) KMT2AMEN1MAPT
SCHEMBL23633289 0.77 KMT2A (0.63) KMT2AMEN1ATMUSP2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629400-B2 Image making medium HYMAN SYDNEY 2009-12-08 US disclosed
US-20030035917-A1 Image making medium HYMAN SYDNEY (US) 2003-02-20 US disclosed