Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | CCR3 | P51677 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4247384 | 1.00 | MCHR1 (0.53) | MCHR1SIGMAR1DRD4CCR3 | |
| SCHEMBL4388557 | 1.00 | MCHR1 (0.53) | MCHR1SIGMAR1DRD4CCR3 | |
| SCHEMBL3149300 | 0.92 | MCHR1 (0.54) | MCHR1SIGMAR1DRD4CCR3 | |
| SCHEMBL4246600 | 0.86 | MCHR1 (0.72) | MCHR1DRD4CCR3 | |
| SCHEMBL4238501 | 0.86 | MCHR1 (0.56) | MCHR1SIGMAR1DRD4CCR3 | |
| SCHEMBL3154070 | 0.83 | MCHR1 (0.54) | MCHR1DRD4CCR3 | |
| SCHEMBL4236492 | 0.83 | DRD4 (0.71) | MCHR1DRD4 | |
| Hydrochloric Acid SCHEMBL4240924 | 0.82 | CCR8 (0.53) | MCHR1SIGMAR1DRD4CCR3 | |
| SCHEMBL3149477 | 0.82 | MCHR1 (0.65) | MCHR1DRD4CCR3 | |
| SCHEMBL4245906 | 0.82 | MCHR1 (0.65) | MCHR1DRD4CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098509-A1 | 1-NAPHTHYL ALKYLPIPERIDINE DERIVATIVE | Taisho Pharmaceutical Co. Ltd. (JP) | 2009-09-09 | — | — | EP | disclosed |