SCHEMBL4388714

SCHEMBL4388714

C/C=C1/CCCCNC1=O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.48
FKBP5 Q13451 1/20 0.48
OR51E2 Q9H255 1/20 0.39
ALDH1A1 P00352 4/20 0.33
GAA P10253 2/20 0.33
GFER P55789 1/20 0.33
PRKD1 Q15139 1/20 0.32
KDM4E B2RXH2 3/20 0.31
ALOX12 P18054 2/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27509858 1.00 CRBN (0.48) CRBNFKBP5OR51E2ALDH1A1GAA
SCHEMBL22382035 0.93
SCHEMBL7588464 0.82
SCHEMBL7588453 0.82
SCHEMBL13065453 0.82
SCHEMBL1264729 0.73 CRBN (0.53) CRBNFKBP5OR51E2ALDH1A1GAA
SCHEMBL18754715 0.73
SCHEMBL725999 0.73
SCHEMBL9680794 0.72
SCHEMBL9680799 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1280768-B1 METHOD FOR PRODUCING CAPROLACTAM FROM 6-AMINOCAPRONITRILE BASF SE (DE) 2009-12-09 EP disclosed
US-6677449-B2 REACTING MIXTURE OF 6-AMINOCAPRONITRILE AND WATER IN LIQUID PHASE IN PRESENCE OF CATALYST, TO GIVE MIXTURE OF CAPROLACTAM, AMMONIA, WATER, AND HIGH AND LOW BOILING COMPONENTS, REMOVING AMMONIA AND WATER, CRYSTALLIZING SOLID CAPROLACTAM BASF AKTIENGESELLSCHAFT (DE) 2004-01-13 US disclosed
EP-1280768-A1 METHOD FOR PRODUCING CAPROLACTAM FROM 6-AMINOCAPRONITRILE BASF AKTIENGESELLSCHAFT (DE) 2003-02-05 EP disclosed
WO-2001083442-A1 METHOD FOR PRODUCING CAPROLACTAM FROM 6-AMINOCAPRONITRILE BASF AKTIENGESELLSCHAFT (DE) 2001-11-08 WO disclosed