Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.61 |
| ▸ | FNTA | P49354 | 2/20 | 0.58 |
| ▸ | FNTB | P49356 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439130 | 1.00 | ACE2 (0.61) | ACE2FNTAFNTBTHRBPGGT1B | |
| SCHEMBL441771 | 1.00 | ACE2 (0.61) | ACE2FNTAFNTBTHRBPGGT1B | |
| SCHEMBL441770 | 1.00 | ACE2 (0.61) | ACE2FNTAFNTBTHRBPGGT1B | |
| SCHEMBL27857612 | 0.89 | FNTA (0.58) | ACE2FNTAFNTBTHRBPGGT1B | |
| SCHEMBL5611268 | 0.89 | FNTA (0.58) | ACE2FNTAFNTBTHRBPGGT1B | |
| SCHEMBL5611253 | 0.89 | FNTA (0.58) | ACE2FNTAFNTBTHRBPGGT1B | |
| SCHEMBL5611258 | 0.89 | FNTA (0.58) | ACE2FNTAFNTBTHRBPGGT1B | |
| SCHEMBL5611265 | 0.89 | FNTA (0.58) | ACE2FNTAFNTBTHRBPGGT1B | |
| SCHEMBL183714 | 0.85 | FNTA (0.75) | FNTAFNTBTHRBPGGT1BFFAR4 | |
| SCHEMBL2902513 | 0.85 | FNTA (0.75) | FNTAFNTBTHRBPGGT1BFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835368-B2 | Compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120065110-A1 | Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |